Evidence map›Paper›PMID 34470838›Full record

Observational studySaudi medical journal2021

Prognostic importance of serum presepsin level in pneumonia focal sepsis and its relationship with other biomarkers and clinical severity scores.

Seda Ozkan, Ugur Kahveci, Izzettin Hur, Ali Halici

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Saudi medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Admission SpOTranslational pediatrics · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Seda OzkanFrom the Department of Emergency Medicine (Ozkan), Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul; from the Department of Emergency Medicine (Kahveci), Eskisehir City Hospital, Eskisehir; from the Department of Emergency Medicine (Hur), Pursaklar State Hospital; and from the Department of Emergency Medicine (Halici), Polatlı State Hospital, Ankara, Turkey.
Ugur KahveciFrom the Department of Emergency Medicine (Ozkan), Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul; from the Department of Emergency Medicine (Kahveci), Eskisehir City Hospital, Eskisehir; from the Department of Emergency Medicine (Hur), Pursaklar State Hospital; and from the Department of Emergency Medicine (Halici), Polatlı State Hospital, Ankara, Turkey.
Izzettin HurFrom the Department of Emergency Medicine (Ozkan), Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul; from the Department of Emergency Medicine (Kahveci), Eskisehir City Hospital, Eskisehir; from the Department of Emergency Medicine (Hur), Pursaklar State Hospital; and from the Department of Emergency Medicine (Halici), Polatlı State Hospital, Ankara, Turkey.
Ali HaliciFrom the Department of Emergency Medicine (Ozkan), Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul; from the Department of Emergency Medicine (Kahveci), Eskisehir City Hospital, Eskisehir; from the Department of Emergency Medicine (Hur), Pursaklar State Hospital; and from the Department of Emergency Medicine (Halici), Polatlı State Hospital, Ankara, Turkey.
Eskişehir City Hospital · TRIstanbul University-Cerrahpaşa · TRState Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo analyze the prognostic value of serum presepsin value in community-acquired pneumonia focal sepsis using sepsis-3 criteria and its relationship with other biomarkers and clinical severity scores.

methodsFor this prospective observational study, 176 patients above 18 years old, diagnosed with community-acquired pneumonia, pneumonia focal sepsis and septic shock were included. It was performed in a tertiary hospital between May 2020 and December 2020. Blood samples were obtained from patients for presepsin levels at the time of diagnosis in the emergency room. The serum presepsin levels of 3 groups were statistically compared with each other.

resultsThe sepsis group had significantly higher serum presepsin levels than the pneumonia group (

conclusionSerum presepsin level is a new biomarker that can be used an indicator of sepsis and mortality in community-acquired pneumonia. However, for determining the prognosis of sepsis, there was no superiority detected over other biomarkers and clinical severity scores.

Indexed as

PneumoniaSepsisAdultBiomarkersHumansLipopolysaccharide ReceptorsPeptide FragmentsPrognosisBiomarkersLipopolysaccharide ReceptorsPeptide Fragmentspresepsin protein, humanmortalitypneumoniapresepsinprognosissepsis

Identifiers

PMID34470838
PMCPMC9280515
OpenAlexW3197952796

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.