Trial reportThe Clinical neuropsychologist2022
Robust demographically-adjusted normative data for the Montreal Cognitive Assessment (MoCA): Results from the systolic blood pressure intervention trial.
Trial report in The Clinical neuropsychologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 28 citations in OpenAlex.
- Exploring the acute and chronic effects of a multistrain probiotic supplement on cognitive function and mood in healthy older adults: a randomized controlled trial.The American journal of clinical nutrition · 2025Trial
- Long-Term Effect of Intensive vs Standard Blood Pressure Control on Mild Cognitive Impairment and Probable Dementia in SPRINT.Neurology · 2025Trial
- Relationships Among Hearing, Auditory Processing, and Cognition: A Study of Older Adults.Audiology research · 2026Article
- Estimation of Montreal Cognitive Assessment Scores Using Caregiver Reports and Demographics: A Model Development Study.Journal of clinical medicine · 2026Article
- The Montreal Cognitive Assessment at the Framingham Heart Study: A Re-Examination of the Norms.Brain and behavior · 2026Article
- Theory of mind predicts conversational success in early right hemisphere stroke recovery.bioRxiv : the preprint server for biology · 2026Article
- Real-world evidence from 50,000 online participants using MoCA-XpressO for cognitive prescreening.Scientific reports · 2026Article
- Exploring resting EEG correlates of age-related hearing difficulties.Frontiers in neuroscience · 2026Article
- Beyond the cut-off: measurement bias, calibration, and fairness in mild cognitive impairment screening.Frontiers in medicine · 2026Article
- CSF estrogens' relationships to neuroinflammatory markers and brain networks in middle-aged and older black and white women.Journal of neuroinflammation · 2025Article
- Nigrostriatal dopaminergic integrity in relation to prefrontal cortex activity and gait performance during dual-task walking in older adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Recalibrating MoCA thresholds in Taiwan: Commentary on new population data.Journal of the Chinese Medical Association : JCMA · 2025Article
- Article
- The Montreal Cognitive Assessment: Norms and Reliable Change Indices for Standard and MoCA-22 Administrations.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Article
- Is the Montreal cognitive assessment culturally valid in a diverse geriatric primary care setting? Lessons from the Bronx.Journal of the American Geriatrics Society · 2024Article
- Association Between Contrast Sensitivity and Physical Function in Cognitively Healthy Older Adults: The Brain Networks and Mobility Function Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Classification statistics of the Montreal Cognitive Assessment (MoCA): Are we interpreting the MoCA correctly?The Clinical neuropsychologist · 2023Article
- Validity of the Brief Assessment of Impaired Cognition case-finding instrument for identification of dementia subgroups and staging of dementia.European journal of neurology · 2023Article
- Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Eliminating racial disparities in dementia risk by equalizing education quality: A sensitivity analysis.Social science & medicine (1982) · 2022Review
Corrections and comments
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Authors and funding
15 authors at 7 institutions in 2 countries.
Funding
Abstract
To generate robust, demographically-adjusted regression-based norms for the Montreal Cognitive Assessment (MoCA) using a large sample of diverse older US adults. Baseline MoCA scores were examined for participants in the Systolic Blood Pressure Intervention Trial (SPRINT). A robust, cognitively-normal sample was drawn from individuals not subsequently adjudicated with cognitive impairment through 4 years of follow-up. Multivariable Beta-Binomial regression was used to model the association of demographic variables with MoCA performance and to create demographically-stratified normative tables. Participants' (N = 5,338) mean age was 66.9 ± 8.8 years, with 35.7% female, 63.1% White, 27.4% Black, 9.5% Hispanic, and 44.5% with a college or graduate education. A large proportion scored below published MoCA cutoffs: 61.4% scored below 26 and 29.2% scored below 23. A disproportionate number falling below these cutoffs were Black, Hispanic, did not graduate from college, or were ≥75 years of age. Multivariable modeling identified education, race/ethnicity, age, and sex as significant predictors of MoCA scores (p<.001), with the best fitting model explaining 24.4% of the variance. Model-based predictions of median MoCA scores were generally 1 to 2 points lower for Black and Hispanic participants across combinations of age, sex, and education. Demographically-stratified norm-tables based on regression modeling are provided to facilitate clinical use, along with our raw data. By using regression-based strategies that more fully account for demographic variables, we provide robust, demographically-adjusted metrics to improve cognitive screening with the MoCA in diverse older adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.