Evidence map›Paper›PMID 34470540›Full record

ReviewPostgraduate medicine2021

Nuts and bolts of COVID-19 associated coagulopathy: the essentials for management and treatment.

Patrick J Lindsay, Rachel Rosovsky, Edward A Bittner, Marvin G Chang

Open access · greenAbstract readReview
In one paragraph

Review in Postgraduate medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Patrick J LindsayDepartment of Critical Care, Cleveland Clinic, Cleveland, Ohio, USA.
Rachel RosovskyDivision of Hematology & Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Edward A BittnerDepartment of Anesthesia Critical Care and Pain, Massachusetts General Hospital, Boston, Massachusetts, USA.
Marvin G ChangDepartment of Anesthesia Critical Care and Pain, Massachusetts General Hospital, Boston, Massachusetts, USA.
Massachusetts General Hospital · USCleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCOVID-19-associated coagulopathy (CAC) is a well-recognized hematologic complication among patients with severe COVID-19 disease, where macro- and micro-thrombosis can lead to multiorgan injury and failure. Major societal guidelines that have published on the management of CAC are based on consensus of expert opinion, with the current evidence available. As a result of limited studies, there are many clinical scenarios that are yet to be addressed, with expert opinion varying on a number of important clinical issues regarding CAC management.

methodsIn this review, we utilize current societal guidelines to provide a framework for practitioners in managing their patients with CAC. We have also provided three clinical scenarios that implement important principles of anticoagulation in patients with COVID-19.

conclusionOverall, decisions should be made on acase by cases basis and based on the providers understanding of each patient's medical history, clinical course and perceived risk.

Indexed as

Practice Guidelines as TopicAnticoagulantsBiomarkersBlood Coagulation DisordersCOVID-19Drug MonitoringFibrinolytic AgentsHemorrhageHeparinHumansPrevalenceThromboembolismThrombosisAnticoagulantsBiomarkersFibrinolytic AgentsHeparinanticoagulationcoronavirusCOVID-19hematologic monitoringtherapeutic anticoagulationthrombosisvenous thromboembolism

Identifiers

PMID34470540
PMCPMC8442752
OpenAlexW3198562028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.