Evidence map›Paper›PMID 34470536›Full record

Trial reportMedical decision making : an international journal of the Society for Medical Decision Making2022

The Impact of 4 Risk Communication Interventions on Cancer Screening Preferences and Knowledge.

K D Valentine, Pete Wegier, Victoria A Shaffer, Laura D Scherer

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medical decision making : an international journal of the Society for Medical Decision Making, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Influence of Anecdotes of IVF Success on Treatment Decision Making: An Online Randomized Controlled Trial.Medical decision making : an international journal of the Society for Medical Decision Making · 2026
    Trial
  3. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

K D ValentineDivision of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-6349-5395
Pete WegierSinai Health, Toronto, ON, Canada.ORCID 0000-0003-0191-136X
Victoria A ShafferUniversity of Missouri, Columbia, MO, USA.ORCID 0000-0002-2533-7115
Laura D SchererUniversity of Colorado, Denver, CO, USA.ORCID 0000-0002-8660-7115
Harvard University · USUniversity of Colorado Denver · USUniversity of Missouri · USUniversity of Toronto · CA

Funding

Understanding affective processing of scientific evidence to promote informed choice for breast cancer screeningR37CA254926 · NCI · UNIVERSITY OF COLORADO DENVER · PI Laura D. Scherer · 2021 to 2026
$3.8M
NCI NIH HHS R37 CA254926
6 · The paper itself

Abstract

purposeThe US Preventive Services Task Force has changed their screening recommendations, encouraging informed patient choice and shared decision making as a result of emerging evidence. We aimed to compare the impact of a didactic intervention, a descriptive harms intervention, a narrative intervention, and a new risk communication strategy titled Aiding Risk Information learning through Simulated Experience (ARISE) on preferences for a hypothetical beneficial cancer screening test (one that reduces the chance of cancer death or extends life) versus a hypothetical screening test with no proven physical benefits.

methodA total of 3386 men and women aged 40 to 70 completed an online survey about prostate or breast cancer screening. Participants were randomly assigned to either an unbeneficial test condition (0 lives saved due to screening) or a beneficial test condition (1 life saved due to screening). Participants then reviewed 4 informational interventions about either breast (women) or prostate (men) cancer screening. First, participants were provided didactic information alongside an explicit recommendation. This was followed by a descriptive harms intervention in which the possible harms of overdetection were explained. Participants then viewed 2 additional interventions: a narrative and ARISE (an intervention in which participants learned about probabilities by viewing simulated outcomes). The order of these last 2 interventions was randomized. Preference for being screened with the test and knowledge about the test were measured.

resultsWith each successive intervention, preferences for screening tests decreased an equivalent amount for both a beneficial and unbeneficial test. Knowledge about the screening tests was largely unimpacted by the interventions.

conclusionsPresenting detailed risk and benefit information, narratives, and ARISE reduced preferences for screening regardless of the net public benefit of screening.

Indexed as

Breast NeoplasmsEarly Detection of CancerCommunicationDecision MakingFemaleHumansMaleMass ScreeningSurveys and Questionnairescancer screeningrisk communicationscreening preferencessimulated experience

Identifiers

PMID34470536
PMCPMC9885623
OpenAlexW3196833216

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.