Evidence map›Paper›PMID 34470498›Full record

ArticleStroke2021

Racial Differences in Blood Pressure Control Following Stroke: The REGARDS Study.

Oluwasegun P Akinyelure, Byron C Jaeger, Tony L Moore, Demetria Hubbard, Suzanne Oparil, Virginia J Howard, George Howard, Joy N Buie, Gayenell S Magwood, Robert J Adams and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Stroke, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  9. Epigenetics as a target to mitigate excess stroke risk in people of African ancestry: A scoping review.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Oluwasegun P AkinyelureDepartment of Epidemiology, School of Public Health (O.P.A., T.L.M., D.H., V.J.H., P.M.), University of Alabama at Birmingham.ORCID 0000-0002-3066-3310
Byron C JaegerDepartment of Biostatistics, School of Public Health (B.C.J., G.H.), University of Alabama at Birmingham.ORCID 0000-0001-7399-2299
Tony L MooreDepartment of Epidemiology, School of Public Health (O.P.A., T.L.M., D.H., V.J.H., P.M.), University of Alabama at Birmingham.ORCID 0000-0003-3854-8453
Demetria HubbardDepartment of Epidemiology, School of Public Health (O.P.A., T.L.M., D.H., V.J.H., P.M.), University of Alabama at Birmingham.ORCID 0000-0002-9165-1874
Suzanne OparilDepartment of Medicine (S.O.), University of Alabama at Birmingham.ORCID 0000-0002-7505-2599
Virginia J HowardDepartment of Epidemiology, School of Public Health (O.P.A., T.L.M., D.H., V.J.H., P.M.), University of Alabama at Birmingham.
George HowardDepartment of Biostatistics, School of Public Health (B.C.J., G.H.), University of Alabama at Birmingham.ORCID 0000-0002-3068-5720
Joy N BuieDepartment of Neurology (J.N.B., R.J.A., L.B., D.T.L.), Medical University of South Carolina, Charleston.
Gayenell S MagwoodDepartment of Nursing (G.S.M.), Medical University of South Carolina, Charleston.ORCID 0000-0002-2451-4888
Robert J AdamsDepartment of Neurology (J.N.B., R.J.A., L.B., D.T.L.), Medical University of South Carolina, Charleston.
Leonardo BonilhaDepartment of Neurology (J.N.B., R.J.A., L.B., D.T.L.), Medical University of South Carolina, Charleston.
Daniel T LacklandDepartment of Neurology (J.N.B., R.J.A., L.B., D.T.L.), Medical University of South Carolina, Charleston.ORCID 0000-0001-5733-6283
Paul MuntnerDepartment of Epidemiology, School of Public Health (O.P.A., T.L.M., D.H., V.J.H., P.M.), University of Alabama at Birmingham.ORCID 0000-0002-4711-5492
University of Alabama at Birmingham · USMedical University of South Carolina · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5M
NIGMS NIH HHS P20 GM109040NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

background and purposeIn the general population, Black adults are less likely than White adults to have controlled blood pressure (BP), and when not controlled, they are at greater risk for stroke compared with White adults. High BP is a major modifiable risk factor for recurrent stroke, but few studies have examined racial differences in BP control among stroke survivors.

methodsWe used data from the REGARDS study (Reasons for Geographic and Racial Differences in Stroke) to examine disparities in BP control between Black and White adults, with and without a history of stroke. We studied participants taking antihypertensive medication who did and did not experience an adjudicated stroke (n=306 and 7693 participants, respectively) between baseline (2003-2007) and a second study visit (2013-2016). BP control at the second study visit was defined as systolic BP <130 mm Hg and diastolic BP <80 mm Hg except for low-risk adults ≥65 years of age (ie, those without diabetes, chronic kidney disease, history of cardiovascular disease, and with a 10-year predicted atherosclerotic cardiovascular disease risk <10%) for whom BP control was defined as systolic BP <130 mm Hg.

resultsAmong participants with a history of stroke, 50.3% of White compared with 39.3% of Black participants had controlled BP. Among participants without a history of stroke, 56.0% of White compared with 50.2% of Black participants had controlled BP. After multivariable adjustment, there was a tendency for Black participants to be less likely than White participants to have controlled BP (prevalence ratio, 0.77 [95% CI, 0.59-1.02] for those with a history of stroke and 0.92 [95% CI, 0.88-0.97] for those without a history of stroke).

conclusionsThere was a lower proportion of controlled BP among Black compared with White adults with or without stroke, with no statistically significant differences after multivariable adjustment.

Indexed as

StrokeAgedBlack or African AmericanBlood PressureFemaleHumansHypertensionMaleMiddle AgedPrevalenceWhite Peopleadultblood pressurehypertensionprevalenceracestroke

Identifiers

PMID34470498
PMCPMC10032619
OpenAlexW3198834359

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.