Evidence map›Paper›PMID 34470094›Full record

ArticleThe Korean journal of parasitology2021

Seroprevalence of Plasmodium vivax Circumsporozoite Protein Antibody in High-Risk Malaria Areas in Korea.

Jinyoung Lee, Kyoung Jin, Seong Kyu Ahn, Sung-Keun Lee, Hyung Wook Kwon, Byoung-Kuk Na, Tong-Soo Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Korean journal of parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Using Serological Markers for the Surveillance ofPathogens (Basel, Switzerland) · 2023
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinyoung LeeDepartment of Parasitology and Tropical Medicine & Global Resource Bank of Parasitic Protozoa Pathogens, Inha University School of Medicine, Incheon 22212, Korea.
Kyoung JinKorea Health Evaluation Institute, Sahmyook University, Seoul 01795, Korea.
Seong Kyu AhnInfectious Diseases Investigation Division, Jeonnam Institute of Public Health and Environment, Muan 58568, Korea.
Sung-Keun LeeDepartment of Pharmacology, Inha University School of Medicine, Incheon, 22212, Korea.
Hyung Wook KwonDepartment of Life Sciences, Incheon National University, Incheon 22012, Korea.
Byoung-Kuk NaDepartment of Parasitology and Tropical Medicine, Department of Convergence Medical Science, and Institute of Health Sciences, Gyeongsang National University College of Medicine, Jinju 52727, Korea.
Tong-Soo KimDepartment of Parasitology and Tropical Medicine & Global Resource Bank of Parasitic Protozoa Pathogens, Inha University School of Medicine, Incheon 22212, Korea.

Funding

Inha University 65321-1National Research Foundation of Korea 2017M3A9B8096530National Research Foundation of Korea 2019K1A3A9A01000005
6 · The paper itself

Abstract

The circumsporozoite protein (CSP) of Plasmodium spp. is a diagnostic antigen and useful biomarker for monitoring short-term/seasonal changes to malaria transmission. Using P. vivax CSP antibody ELISA, epidemiological characteristics were analyzed in the residents of Ganghwa, Cheorwon, Paju, and Goseong from 2017 to 2018. In Ganghwa and Cheorwon, 1.6% and 1.2% of residents, respectively, were PvCSP-antibody-positive in 2018, which indicates a decrease of 0.4% in the positive rate compared to 2017. The annual parasite incidence (API) in Ganghwa and Cheorwon was 24.9 and 10.5 in 2017 and 20.3 and 10.7 in 2018, respectively. Although the changes were not significant, the API in Ganghwa decreased slightly by 4.5 in 2018 compared to the previous year. In Paju and Goseong, 3.9% and 2.0% of residents were positive for the PvCSP antibody. The API in Paju was 13.1 in 2017 and 16.0 in 2018, although no malaria patients were reported for the 2 years. Therefore, the results suggest that PvCSP is a useful antigen for confirming initial malaria infection. Additionally, considering that the antibody is relatively transient, it can be employed for sero-epidemiological studies to determine the extent of malaria transmission in the current year.

Indexed as

MalariaMalaria, VivaxAntibodies, ProtozoanHumansPlasmodium vivaxProtozoan ProteinsRepublic of KoreaSeroepidemiologic StudiesAntibodies, ProtozoanProtozoan Proteinscircumsporozoite proteinelimination studyKoreaPlasmodium vivaxvivax malaria

Identifiers

PMID34470094
PMCPMC8413862

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.