ArticleThe Korean journal of parasitology2021
Anticoccidial Activity of Berberine against Eimeria-Infected Chickens.
Article in The Korean journal of parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Insights into Non-Antibiotic Alternative and Emerging Control Strategies for Chicken Coccidiosis.Animals : an open access journal from MDPI · 2026Review
- UnderstandingFrontiers in cellular and infection microbiology · 2026Review
- Vaccinations and Functional Feed Supplements as Alternatives to Coccidiostats for the Control of Coccidiosis in Raising Broiler Chickens.Animals : an open access journal from MDPI · 2025Review
- Berberine Reveals Anticoccidial Activity by Influencing Immune Responses inBiomolecules · 2025Article
- Evaluation of the Effectiveness of a Phytogenic Supplement (Alkaloids and Flavonoids) in the Control ofAnimals : an open access journal from MDPI · 2025Article
- Large-Scale Field Trials of anVaccines · 2024Article
- Management and control of coccidiosis in poultry - A review.Animal bioscience · 2024Article
- The Immunoprotective Effect of ROP27 Protein ofAnimals : an open access journal from MDPI · 2023Article
- Pathological Role of Oxidative Stress in Aflatoxin-Induced Toxicity in Different Experimental Models and Protective Effect of Phytochemicals: A Review.Molecules (Basel, Switzerland) · 2023Review
- Botanicals: A promising approach for controlling cecal coccidiosis in poultry.Frontiers in veterinary science · 2023Review
- Epidemiological investigation and drug resistance of Eimeria species in Korean chicken farms.BMC veterinary research · 2022Article
- Oral administration of Lactobacillus brevis 23017 combined with ellagic acid attenuates intestinal inflammatory injury caused by Eimeria infection by activating the Nrf2/HO-1 antioxidant pathway.Veterinary research · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Avian coccidiosis has a major economic impact on the poultry industry, it is caused by 7 species of Eimeria, and has been primarily controlled using chemotherapeutic agents. Due to the emergence of drug-resistant strains, alternative control strategies are needed. We assessed anticoccidial effects of berberine-based diets in broiler chickens following oral infection with 5 Eimeria species (E. acervulina, E. maxima, E. tenella, E. mitis, and E. praecox). When 0.2% berberine, a concentration that does not affect weight gain, was added to the diet, the 4 groups infected with E. acervulina, E. tenella, E. mitis, or E. praecox showed significant reductions in fecal oocyst shedding (P<0.05) compared to their respective infected and untreated controls. In chickens treated 0.5% berberine instead of 0.2% and infected with E. maxima, fecal oocyst production was significantly reduced, but body weight deceased, indicating that berberine treatment was not useful for E. maxima infection. Taken together, these results illustrate the applicability of berberine for prophylactic use to control most Eimeria infections except E. maxima. Further studies on the mechanisms underlying the differences in anticoccidial susceptibility to berberine, particularly E. maxima, are remained.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.