Evidence map›Paper›PMID 34469921›Full record

ArticleAmerican journal of therapeutics2021

Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines. American Journal of Therapeutics, 28, e434-e460, July 2021.

Andrew Bryant, Theresa A Lawrie, Edmund J Fordham

Abstract readLetterComment
In one paragraph

Article in American journal of therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Ivermectin for preventing and treating COVID-19.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Andrew BryantNewcastle University, Population Health Sciences Institute, Newcastle-upon-Tyne, United Kingdom.
Theresa A LawrieEvidence-Based Medicine Consultancy Ltd, and EbMCsquared, a Community Interest Company Northgate House, Upper Borough Walls, Bath, United Kingdom.
Edmund J FordhamEvidence-Based Medicine Consultancy Ltd, and EbMCsquared, a Community Interest Company Northgate House, Upper Borough Walls, Bath, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19IvermectinAntiviral AgentsHumansSARS-CoV-2Treatment OutcomeUnited StatesAntiviral AgentsIvermectin

Identifiers

PMID34469921
PMCPMC8415517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.