Evidence map›Paper›PMID 34469558›Full record

ArticleThe Journal of infectious diseases2021

Triplex Direct Quantitative Polymerase Chain Reaction for the Identification of Streptococcus pneumoniae Serotypes.

Mahamoudou Ouattara, Mamadou Tamboura, Dinanibè Kambiré, Kim Anh Lê, Thanh Van Phan, Srinivasan Velusamy, Hien Anh Nguyen, Dai Vo Thi Trang, Fernanda C Lessa, Makiko Iijima and 5 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  5. Development of a Molecular Serotyping Scheme forFrontiers in microbiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Mahamoudou OuattaraDivision of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Mamadou TambouraCentre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouagadougou, Burkina Faso.
Dinanibè KambiréCentre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouagadougou, Burkina Faso.
Kim Anh LêNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Thanh Van PhanPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Srinivasan VelusamyDivision of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Hien Anh NguyenNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Dai Vo Thi TrangPasteur Institute of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Fernanda C LessaDivision of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Makiko IijimaWorld Health Organization Representative Office for Vietnam, Expanded Programme on Immunization, Hanoi, Vietnam.
Dac Trung NguyenNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Stephanie B SchwartzDivision of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Lesley McGeeDivision of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Rasmata Ouédraogo TraoréCentre Hospitalier Universitaire Pédiatrique Charles de Gaulle, Ouagadougou, Burkina Faso.
Bernard BeallDivision of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0001-5315-1070
Centers for Disease Control and Prevention · USCentre Hospitalier Universitaire Yalgado Ouédraogo · BFNational Institute Of Hygiene And Epidemiology · VNInstitut Pasteur in Ho Chi Minh City · VN

Funding

World Health Organization 001
6 · The paper itself

Abstract

The quantitative polymerase chain reaction (qPCR) method presented in this study allows the identification of pneumococcal capsular serotypes in cerebrospinal fluid without first performing DNA extraction. This testing approach, which saves time and resources, demonstrated similar sensitivity and a high level of agreement between cycle threshold values when it was compared side-by-side with the standard qPCR method with extracted DNA.

Indexed as

Pneumococcal InfectionsHumansMultiplex Polymerase Chain ReactionSerogroupSerotypingStreptococcus pneumoniaedirect real-time PCRpneumococcal serotypeStreptococcus pneumoniae

Identifiers

PMID34469558
PMCPMC8414907
OpenAlexW3197832343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.