Evidence map›Paper›PMID 34469103›Full record

ArticleACS applied materials & interfaces2021

Plasmonic Metasurfaces Based on Pyramidal Nanoholes for High-Efficiency SERS Biosensing.

Giovanna Palermo, Massimo Rippa, Ylli Conti, Ambra Vestri, Riccardo Castagna, Giovanna Fusco, Elisabetta Suffredini, Jun Zhou, Joseph Zyss, Antonio De Luca and 1 more

Open access · hybridAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Metasurface-enhanced biomedical spectroscopy.Nanophotonics (Berlin, Germany) · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Raman Scattering Enhancement through Pseudo-Cavity Modes.Nanomaterials (Basel, Switzerland) · 2024
    Article
  12. Applications of Gold Nanoparticles in Plasmonic and Nanophotonic Biosensing.Advances in biochemical engineering/biotechnology · 2024
    Review
  13. Review
  14. Review
  15. Direct Bottom-UpChemical reviews · 2023
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Giovanna PalermoDepartment of Physics, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.ORCID https://orcid.org/0000-0001-5649-735X
Massimo RippaInstitute of Applied Sciences and Intelligent Systems "E. Caianiello" CNR, 80078 Pozzuoli, Italy.ORCID https://orcid.org/0000-0002-1993-4589
Ylli ContiDepartment of Physics, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.
Ambra VestriInstitute of Applied Sciences and Intelligent Systems "E. Caianiello" CNR, 80078 Pozzuoli, Italy.
Riccardo CastagnaInstitute of Applied Sciences and Intelligent Systems "E. Caianiello" CNR, 80078 Pozzuoli, Italy.
Giovanna FuscoDepartment of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanitá, 00161 Rome, Italy.
Elisabetta SuffrediniDepartment of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanitá, 00161 Rome, Italy.
Jun ZhouInstitute of Photonics, Faculty of Science, Ningbo University, 315211 Ningbo, People's Republic of China.
Joseph ZyssLUMIN Laboratory (CNRS), Institut d'Alembert, Universitè Paris Saclay, 91190 Gif sur Yvette, France.
Antonio De LucaDepartment of Physics, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy.ORCID https://orcid.org/0000-0003-2428-9075
Lucia PettiInstitute of Applied Sciences and Intelligent Systems "E. Caianiello" CNR, 80078 Pozzuoli, Italy.
Institute of Applied Science and Intelligent Systems · ITIstituto di Nanotecnologia · ITIstituto Superiore di Sanità · ITCentre National de la Recherche Scientifique · FRNingbo University · CNUniversity of Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An inverted pyramidal metasurface was designed, fabricated, and studied at the nanoscale level for the development of a label-free pathogen detection on a chip platform that merges nanotechnology and surface-enhanced Raman scattering (SERS). Based on the integration and synergy of these ingredients, a virus immunoassay was proposed as a relevant proof of concept for very sensitive detection of hepatitis A virus, for the first time to our best knowledge, in a very small volume (2 μL), without complex signal amplification, allowing to detect a minimal virus concentration of 13 pg/mL. The proposed work aims to develop a high-flux and high-accuracy surface-enhanced Raman spectroscopy (SERS) nanobiosensor for the detection of pathogens to provide an effective method for early and easy water monitoring, which can be fast and convenient.

Indexed as

NanoporesAntibodies, ImmobilizedAntibodies, ViralBiosensing TechniquesGoldHepatitis A virusImmunoassayProof of Concept StudySpectrum Analysis, RamanWater MicrobiologyAntibodies, ImmobilizedAntibodies, ViralGoldbiosensinghepatitis A virusmetasurfaceplasmonicspyramidal nanoholessurface-enhanced Raman scattering

Identifiers

PMID34469103
PMCPMC8447193
OpenAlexW3196290835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.