ReviewCurrent atherosclerosis reports2021
Lipid Phenotypes and DNA Methylation: a Review of the Literature.
Review in Current atherosclerosis reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- DNA Methylation Near CPT1A and Changes in Triglyceride-rich Lipoproteins in Response to Weight-loss Diet Interventions.The Journal of clinical endocrinology and metabolism · 2023Trial
- Global DNA methylation and hypertension control Vis-À-Vis lipids: an exploratory population based study from rural Punjab, India.Journal of human hypertension · 2026Article
- Simultaneous Assessment of Genetic and Epigenetic Contributions to the Plasma Lipid Levels with Respect to Cardiovascular Risk.Journal of atherosclerosis and thrombosis · 2026Article
- Dose-response relationships of normal blood lipid levels in metabolic and endocrine diseases: mechanistic similarities, differences, and functional insights.Frontiers in endocrinology · 2026Review
- Blood and adipose tissue DNA methylation in adults born preterm with a very low birth weight - a sibling comparison study.Epigenomics · 2026Article
- Methylome-wide association analyses of lipids and modifying effects of behavioral factors in diverse race and ethnicity participants.Clinical epigenetics · 2025Article
- Longitudinal association between DNA methylation and type 2 diabetes: findings from the KORA F4/FF4 study.Cardiovascular diabetology · 2025Article
- Multi-Omics Insights into Regulatory Mechanisms Underlying Differential Deposition of Intramuscular and Abdominal Fat in Chickens.Biomolecules · 2025Review
- Epigenetic changes in pyloric caeca of Atlantic salmon fed diets containing increasing levels of lipids and choline.Epigenetics · 2024Article
- Lipid Metabolism, Methylation Aberrant, and Osteoporosis: A Multi-omics Study Based on Mendelian Randomization.Calcified tissue international · 2024Article
- Methylation status ofEpigenomics · 2024Article
- DNA Methylation at ABCG1 and Long-term Changes in Adiposity and Fat Distribution in Response to Dietary Interventions: The POUNDS Lost Trial.Diabetes care · 2023Article
- Blood-based genome-wide DNA methylation correlations across body-fat- and adiposity-related biochemical traits.American journal of human genetics · 2023Article
- The potential role and mechanism of circRNAs in foam cell formation.Non-coding RNA research · 2023Review
- Toward Precision Weight-Loss Dietary Interventions: Findings from the POUNDS Lost Trial.Nutrients · 2023Review
- Epigenome-wide association study of plasma lipids in West Africans: the RODAM study.EBioMedicine · 2023Article
- Metabolite profiles and DNA methylation in metabolic syndrome: a two-sample, bidirectional Mendelian randomization.Frontiers in genetics · 2023Article
- Epigenetic Mechanisms of Endocrine-Disrupting Chemicals in Obesity.Biomedicines · 2021Review
- Subclinical Vascular Damage: Current Insights and Future Potential.Vascular health and risk management · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purpose of reviewEpigenetic modifications via DNA methylation have previously been linked to blood lipid levels, dyslipidemias, and atherosclerosis. The purpose of this review is to discuss current literature on the role of DNA methylation on lipid traits and their associated pathologies. RECENT
findingsCandidate gene and epigenome-wide approaches have identified differential methylation of genes associated with lipid traits (particularly CPT1A, ABCG1, SREBF1), and novel approaches are being implemented to further characterize these relationships. Moreover, studies on environmental factors have shown that methylation variations at lipid-related genes are associated with diet and pollution exposure. Further investigation is needed to elucidate the directionality of the associations between the environment, lipid traits, and epigenome. Future studies should also seek to increase the diversity of cohorts, as European and Asian ancestry populations are the predominant study populations in the current literature.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.