ArticleEuropean heart journal2021
Determinants of outcomes following surgery for type A acute aortic dissection: the UK National Adult Cardiac Surgical Audit.
Article in European heart journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Searching Optimal Tailored Strategy for Repair of Acute Type A Acute Aortic Dissection
Early Complication and Outcomes in Surgical vs no Surgical Involvement of Aortic Arch in Type A Aortic Dissection
Surgical Strategy for Repair of Aortic Dissection: A Multicenter Registry
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Acute type A aortic dissection in patients with non-prior cardiac surgery vs. prior cardiac surgery: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Therapeutic Efficacy of Sivelestat Sodium in ARDS Following Aortic Dissection: A Pilot Physiological Trial with Exploratory Transcriptomic Analysis.Journal of inflammation research · 2026Trial
- Laboratory signatures differentiate the tolerance to hypothermic circulatory arrest in acute type A aortic dissection surgery.Interactive cardiovascular and thoracic surgery · 2022Trial
- The Aorta Is One Organ; Our Response Is Not: A Global Case for Systems Redesign in Acute Aortic Syndromes.Journal of clinical medicine · 2026Review
- From routine to rescue: Higher elective aortic surgery volume is associated with improved outcomes after acute type A aortic dissection repair.JTCVS open · 2026Article
- CT angiography features of organ malperfusion and imaging biomarker for postoperative adverse complications in acute type A aortic dissection.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Frozen elephant trunk: a narrative review of global and temporal trends.Journal of thoracic disease · 2026Review
- Article
- Regional travel distance is not associated with operative mortality in acute type A aortic dissection.JTCVS open · 2026Article
- Impact of an On-Call Specialist Aortic Rota Implementation in Acute Type a Aortic Dissection on Outcomes and Repair Complexity: A Retrospective Cohort Study.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Interfacility Transfer and Early Mortality in Type A Acute Aortic Dissection: A Multicenter Registry Study.JACC. Asia · 2025Article
- Neutrophil Percentage to Albumin Ratio Is Associated With In-Hospital Mortality in Patients With Acute Type A Aortic Dissection.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Total aortic arch replacement versus proximal aortic repair for acute type a aortic dissection: A single-center 30-year experience.JTCVS open · 2025Article
- Aortic lumen repair with glue-felt technique before proximal anastomosis in acute type a aortic dissection surgery.Journal of cardiothoracic surgery · 2025Article
- Risk factors and clinical outcomes of severe postoperative hypoxaemia following surgical repair of Stanford type A aortic dissection: a retrospective cohort study.Frontiers in medicine · 2025Article
- Contemporary comparative surgical outcomes of type A aortic dissection in US and China: an analysis of the national inpatient sample database and a Chinese multi-institutional registry.Journal of cardiothoracic surgery · 2024Article
- Time critical diagnoses and transfers of patients with acute type A aortic dissection in the UK: national audit of current practice.Anaesthesia · 2024Article
- Aortic arch registry of type a aortic dissection (AoArch) - rationale, design and definition criteria.Journal of cardiothoracic surgery · 2024Observational
- Aortic arch surgery for DeBakey type 1 aortic dissection in patients aged 60 years or younger.BJS open · 2024Article
- Study on risk factors and treatment strategies of hypoxemia after acute type a aortic dissection surgery.Journal of cardiothoracic surgery · 2024Review
Corrections and comments
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Authors and funding
18 authors at 13 institutions in 1 country.
Funding
Abstract
aimsOperability of type A acute aortic dissections (TAAAD) is currently based on non-standardized decision-making process, and it lacks a disease-specific risk evaluation model that can predict mortality. We investigated patient, intraoperative data, surgeon, and centre-related variables for patients who underwent TAAAD in the UK. METHODS AND
resultsWe identified 4203 patients undergoing TAAAD surgery in the UK (2009-18), who were enrolled into the UK National Adult Cardiac Surgical Audit dataset. The primary outcome was operative mortality. A multivariable logistic regression analysis was performed with fast backward elimination of variables and the bootstrap-based optimism-correction was adopted to assess model performance. Variation related to hospital or surgeon effects were quantified by a generalized mixed linear model and risk-adjusted funnel plots by displaying the individual standardized mortality ratio against expected deaths. Final variables retained in the model were: age [odds ratio (OR) 1.02, 95% confidence interval (CI) 1.02-1.03; P < 0.001]; malperfusion (OR 1.79, 95% CI 1.51-2.12; P < 0.001); left ventricular ejection fraction (moderate: OR 1.40, 95% CI 1.14-1.71; P = 0.001; poor: OR 2.83, 95% CI 1.90-4.21; P < 0.001); previous cardiac surgery (OR 2.29, 95% CI 1.71-3.07; P < 0.001); preoperative mechanical ventilation (OR 2.76, 95% CI 2.00-3.80; P < 0.001); preoperative resuscitation (OR 3.36, 95% CI 1.14-9.87; P = 0.028); and concomitant coronary artery bypass grafting (OR 2.29, 95% CI 1.86-2.83; P < 0.001). We found a significant inverse relationship between surgeons but not centre annual volume with outcomes.
conclusionsPatient characteristics, intraoperative factors, cardiac centre, and high-volume surgeons are strong determinants of outcomes following TAAAD surgery. These findings may help refining clinical decision-making, supporting patient counselling and be used by policy makers for quality assurance and service provision improvement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.