Evidence map›Paper›PMID 34468194›Full record

ArticleMicrobiology spectrum2021

An Ohio State Scenic River Shows Elevated Antibiotic Resistance Genes, Including Acinetobacter Tetracycline and Macrolide Resistance, Downstream of Wastewater Treatment Plant Effluent.

April Murphy, Daniel Barich, M Siobhan Fennessy, Joan L Slonczewski

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  6. Review
  7. Distribution ofPathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

April MurphyDepartment of Biology, Kenyon Collegegrid.258533.a, Gambier, Ohio, USA.
Daniel BarichDepartment of Biology, Kenyon Collegegrid.258533.a, Gambier, Ohio, USA.
M Siobhan FennessyDepartment of Biology, Kenyon Collegegrid.258533.a, Gambier, Ohio, USA.
Joan L SlonczewskiDepartment of Biology, Kenyon Collegegrid.258533.a, Gambier, Ohio, USA.ORCID 0000-0003-3484-1564
Kenyon College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The entry of antibiotic resistance genes (ARGs) into aquatic systems has been documented for large municipal wastewater treatment plants (WWTPs), but there is less study of the impact of smaller plants that are situated on small rural rivers. We sampled water metagenomes for ARGs and taxa composition from the Kokosing River, a small rural river in Knox County, Ohio, which has been designated an Ohio State Scenic River for retention of natural character. Samples were obtained 1.0 km upstream, 120 m downstream, and 6.4 km downstream from the effluent release of the Mount Vernon WWTP. ARGs were identified in metagenomes using ShortBRED markers from the comprehensive antibiotic resistance database (CARD) screened against UniPROT. Through all seasons, the metagenome just downstream of the WWTP effluent showed a substantial elevation of at least 15 different ARGs, including 6 ARGs commonly associated with Acinetobacter baumannii, such as

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsBacillotaBacteroidesDrug Resistance, Multiple, BacterialHumansMacrolidesMetagenomeMicrobiotaOhioPhylogenyRiversTetracyclinesWastewaterWater PurificationAnti-Bacterial AgentsMacrolidesTetracyclinesWastewaterAcinetobacterantibiotic resistancemetagenomemicrobiomeriverwastewater

Identifiers

PMID34468194
PMCPMC8557926
OpenAlexW3196922465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.