Evidence map›Paper›PMID 34468091›Full record

ArticleChemistryOpen2021

First Isolation and Structure Elucidation of GDNT-β-Glu - Tetraether Lipid Fragment from Archaeal Sulfolobus Strains.

Alexander Scholte, Christoph Hübner, Dieter Ströhl, Olaf Scheufler, Steffen Czich, Julia M Börke, Gerhard Hildebrand, Klaus Liefeith

Open access · goldAbstract read
In one paragraph

Article in ChemistryOpen, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Alexander ScholteInstitute for Bioprocessing and Analytical Measurement Techniques, Rosenhof, 37308, Heilbad Heiligenstadt, Germany.
Christoph HübnerInstitute for Bioprocessing and Analytical Measurement Techniques, Rosenhof, 37308, Heilbad Heiligenstadt, Germany.
Dieter StröhlDepartment of Chemistry, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 2, 06120, Halle, Germany.
Olaf ScheuflerIFB Halle, Schiepziger Straße 35, 06120, Halle/Saale, Germany.
Steffen CzichInstitute for Bioprocessing and Analytical Measurement Techniques, Rosenhof, 37308, Heilbad Heiligenstadt, Germany.
Julia M BörkeInstitute for Bioprocessing and Analytical Measurement Techniques, Rosenhof, 37308, Heilbad Heiligenstadt, Germany.
Gerhard HildebrandInstitute for Bioprocessing and Analytical Measurement Techniques, Rosenhof, 37308, Heilbad Heiligenstadt, Germany.
Klaus LiefeithInstitute for Bioprocessing and Analytical Measurement Techniques, Rosenhof, 37308, Heilbad Heiligenstadt, Germany.
Institute for Bioprocessing and Analytical Measurement Techniques · DEHalle Institute for Economic Research · DEMartin Luther University Halle-Wittenberg · DE

Funding

Bundesministerium für Bildung und Forschung (Germany) 03XP0044EBundesministerium für Bildung und Forschung (Germany) 13GW0082E
6 · The paper itself

Abstract

Due to their special chemical structure, tetraether lipids (TEL) represent essential elements of archaeal membranes, providing these organisms with extraordinary properties. Here we describe the characterization of a newly isolated structural element of the main lipids. The TEL fragment GDNT-β-Glu was isolated from Sulfolobus metallicus and characterized in terms of its chemical structure by NMR- and MS-investigations. The obtained data are dissimilar to analogically derived established structures - in essence, the binding relationships in the polar head group are re-determined and verified. With this work, we provide an important contribution to the structure elucidation of intact TEL also contained in other Sulfolobus strains such as Solfulobus acidocaldarius and Sulfolobus solfataricus.

Indexed as

Carbon-13 Magnetic Resonance SpectroscopyCyclizationDiglyceridesGlycolipidsMass SpectrometryMembrane LipidsSulfolobuscalditoglycerocaldarchaeolDiglyceridesGlycolipidsMembrane Lipidsarchaeamass spectrometryNMR spectroscopystructure elucidationtetraether lipids

Identifiers

PMID34468091
PMCPMC8409090
OpenAlexW3197299031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.