Evidence map›Paper›PMID 34468011›Full record

ArticleOncology reports2021

Development of patient‑derived tumor organoids and a drug testing model for renal cell carcinoma.

Akira Kazama, Tsutomu Anraku, Hiroo Kuroki, Yuko Shirono, Masaki Murata, Vladimir Bilim, Andrey Ugolkov, Kazuhide Saito, Yoshihiko Tomita

Abstract read
In one paragraph

Article in Oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Endoplasmic Reticulum Stress in Renal Cell Carcinoma.International journal of molecular sciences · 2023
    Review
  12. Organoids: opportunities and challenges of cancer therapy.Frontiers in cell and developmental biology · 2023
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akira KazamaDepartment of Urology, Division of Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951‑8510, Japan.
Tsutomu AnrakuDepartment of Urology, Division of Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951‑8510, Japan.
Hiroo KurokiDepartment of Urology, Division of Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951‑8510, Japan.
Yuko ShironoDepartment of Urology, Division of Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951‑8510, Japan.
Masaki MurataDepartment of Urology, Division of Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951‑8510, Japan.
Vladimir BilimDepartment of Urology, Division of Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951‑8510, Japan.
Andrey UgolkovActuate Therapeutics, Inc., Fort Worth, TX 76107, USA.
Kazuhide SaitoDepartment of Urology, Division of Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951‑8510, Japan.
Yoshihiko TomitaDepartment of Urology, Division of Molecular Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951‑8510, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The selection of effective therapeutic agents is critical for improving the survival of patients with renal cell carcinoma (RCC). The aim of the present study was to develop an

Indexed as

Carcinoma, Renal CellCell Line, TumorHumansOrganoidsProtein Kinase InhibitorsReceptor Protein-Tyrosine KinasesProtein Kinase InhibitorsReceptor Protein-Tyrosine Kinasespersonalized therapyprecision medicinerenal cell carcinomatumor organoid

Identifiers

PMID34468011
PMCPMC8424486

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.