Evidence map›Paper›PMID 34467774›Full record

ArticleFuture oncology (London, England)2021

A plain language summary of the ASCENT study: Sacituzumab Govitecan for metastatic triple-negative breast cancer.

Aditya Bardia, Sara A Hurvitz, Hope S Rugo, Adam Brufsky, Javier Cortes, Sibylle Loibl, M Piccart, Janice Cowden, Patty Spears, Lisa A Carey

Open access · hybridAbstract readCommentPatient Education Handout
PubMed Publisher
In one paragraph

Article in Future oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
  7. Trophoblast Cell Surface Antigen 2 Expression in Human Tumors: A Tissue Microarray Study on 18,563 Tumors.Pathobiology : journal of immunopathology, molecular and cellular biology · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 4 countries.

Aditya BardiaMassachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
Sara A HurvitzUniversity of California, Los Angeles, Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA.
Hope S RugoUniversity of California, San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.
Adam BrufskyMagee-Women's Hospital and the Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Javier CortesInternational Breast Cancer Center (IBCC), Quiron Group, Barcelona, Spain.
Sibylle LoiblDepartment of Medicine and Research, Hämatologisch-Onkologische Gemeinschaftspraxis am Bethanien-Krankenhaus, Frankfurt, Germany.
M PiccartInstitut Jules Bordet, Université libre de Bruxelles, Brussels, Belgium.
Janice CowdenPatient author.
Patty SpearsPatient author.
Lisa A CareyDepartment of Medicine - Division of Hematology/Oncology, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USCenter for Cancer Research · USInstitut Jules Bordet · BEInternational Breast Cancer Study Group · CHKrankenhaus Bethanien · DENational Patient Safety Foundation · USUCSF Helen Diller Family Comprehensive Cancer Center · USUPMC Hillman Cancer Center · USUSC Norris Comprehensive Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sacituzumab Govitecan (also known by the brand name TRODELVY

Indexed as

ImmunoconjugatesTriple Negative Breast NeoplasmsAntibodies, Monoclonal, HumanizedCamptothecinHumansLanguageAntibodies, Monoclonal, HumanizedCamptothecinImmunoconjugatessacituzumab govitecanantibody–drug conjugatebreast cancerlay summaryplain language summarySacituzumab Govitecantriple-negative breast cancerTrop-2

Identifiers

PMID34467774
OpenAlexW3198493057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.