Evidence map›Paper›PMID 34467764›Full record

ArticleJournal of the American Chemical Society2021

Reactivity and DNA Damage by Independently Generated 2'-Deoxycytidin-

Haihui Peng, Jialong Jie, Ifor P Mortimer, Zehan Ma, Hongmei Su, Marc M Greenberg

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Investigating DNA damage caused by COVID-19 and influenza in post COVID-19.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Article
  4. 8-OxodGuo and Fapy•dG Mutagenicity inChemical research in toxicology · 2024
    Article
  5. Nitrogen-Centered Radicals Derived from Azidonucleosides.Molecules (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The potential role of COVID-19 in the induction of DNA damage.Mutation research. Reviews in mutation research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Haihui PengDepartment of Chemistry, Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States.ORCID 0000-0002-1989-5508
Jialong JieCollege of Chemistry, Beijing Normal University, Beijing 100875, P. R. China.
Ifor P MortimerDepartment of Chemistry, Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States.
Zehan MaCollege of Chemistry, Beijing Normal University, Beijing 100875, P. R. China.
Hongmei SuCollege of Chemistry, Beijing Normal University, Beijing 100875, P. R. China.ORCID 0000-0001-7384-6523
Marc M GreenbergDepartment of Chemistry, Johns Hopkins University, 3400 N. Charles Street, Baltimore, Maryland 21218, United States.ORCID 0000-0002-5786-6118
Beijing Normal University · CNJohns Hopkins University · US

Funding

How Damaged DNA Forms, and its Subsequent Chemistry: Fundamental Studies and ApplicationsR35GM131736 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI MARC M GREENBERG · 2019 to 2026
$4.3M
NIGMS NIH HHS R35 GM131736
6 · The paper itself

Abstract

Oxidative stress produces a variety of radicals in DNA, including pyrimidine nucleobase radicals. The nitrogen-centered DNA radical 2'-deoxycytidin-

Indexed as

DeoxycytidineDeoxyguanosineDNADNA DamageFree RadicalsOximesPhotolysisUltraviolet RaysDeoxycytidineDeoxyguanosineDNAFree RadicalsOximes

Identifiers

PMID34467764
PMCPMC8728764
OpenAlexW3197609878

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.