ArticleAdvanced materials (Deerfield Beach, Fla.)2021
Bioinspired Functionally Graded Composite Assembled Using Cellulose Nanocrystals and Genetically Engineered Proteins with Controlled Biomineralization.
Article in Advanced materials (Deerfield Beach, Fla.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Biomolecular coacervation-mediated materials: Phase states, phase transitions, and biomedical applications.Bioactive materials · 2027Review
- A natural solution from caterpillar cuticles for flexible impact-resistant materials.Nature communications · 2026Article
- Morphologically Guided Mesoscopic Pore System for Enhancing the Impact Resistance of Stomatopod Telson.Chem & bio engineering · 2026Article
- Biosynthetic optical waveguide interface integration using biomimetic -Computational and structural biotechnology journal · 2026Article
- Design and Heterologous Production of Bagworm Silk-Inspired Proteins inComputational and structural biotechnology journal · 2026Article
- Functional Biomaterials Derived from Protein Liquid-Liquid Phase Separation and Liquid-to-Solid Transition.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Biomaterials-mediated biomineralization for tumor blockade therapy.Nanomedicine (London, England) · 2025Review
- Tailoring hydrophobicity and strength in spider silk-inspired coatings via thermal treatments.Computational and structural biotechnology journal · 2024Article
- Physical Unclonable Functions with Hyperspectral Imaging System for Ultrafast Storage and Authentication Enabled by Random Structural Color Domains.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- A Bioinspired Design of Protective AlAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Research progress of biomimetic materials in oral medicine.Journal of biological engineering · 2023Review
- Protein-Based Biological Materials: Molecular Design and Artificial Production.Chemical reviews · 2023Review
- The complex structure ofScience advances · 2023Article
- Bioinspired Functionally Graded Composite Assembled Using Cellulose Nanocrystals and Genetically Engineered Proteins with Controlled Biomineralization.Advanced materials (Deerfield Beach, Fla.) · 2021Article
- Methylcellulose-Cellulose Nanocrystal Composites for Optomechanically Tunable Hydrogels and Fibers.Materials (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Nature provides unique insights into design strategies evolved by living organisms to construct robust materials with a combination of mechanical properties that are challenging to replicate synthetically. Hereby, inspired by the impact-resistant dactyl club of the stomatopod, a mineralized biocomposite is rationally designed and produced in the complex shapes of dental implant crowns exhibiting high strength, stiffness, and fracture toughness. This material consists of an expanded helicoidal organization of cellulose nanocrystals (CNCs) mixed with genetically engineered proteins that regulate both binding to CNCs and in situ growth of reinforcing apatite crystals. Critically, the structural properties emerge from controlled self-assembly across multiple length scales regulated by rational engineering and phase separation of the protein components. This work replicates multiscale biomanufacturing of a model biological material and also offers an innovative platform to synthesize multifunctional biocomposites whose properties can be finely regulated by colloidal self-assembly and engineering of its constitutive protein building blocks.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.