ReviewAmerican journal of hematology2021
Recommendations for diagnosis and treatment of methemoglobinemia.
Review in American journal of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
106 citing papers in PubMed, 1 synthesis or guideline pooled it, 205 citations in OpenAlex.
- Recessive congenital methemoglobinemia: a systematic review of reported cases.Orphanet journal of rare diseases · 2026Pooled it
- A safety evaluation of intermittent high-dose inhaled nitric oxide in viral pneumonia due to COVID-19: a randomised clinical study.Scientific reports · 2024Trial
- A Comprehensive Review of the Approach to Ultrasonography in Neonatal Shock: The Partnership Between Targeted Neonatal Echocardiography and Point-of-Care Ultrasound.Children (Basel, Switzerland) · 2026Review
- Methaemoglobinaemia: From pathophysiology to contemporary clinical management.British journal of haematology · 2026Review
- Article
- [Whole blood exchange for a critically ill patient with Hodgkin lymphoma complicated by severe autoimmune hemolytic anemia: a case report and literature review].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2026Review
- Methemoglobinemia in Infancy.Annals of African medicine · 2026Article
- A Case Series of Acquired Methemoglobinemia in Infants.Indian pediatrics · 2026Article
- The long tail of nitrate pollution in groundwater challenges governance of global water quality.Nature communications · 2026Article
- Hereditary methemoglobinemia diagnosed in adulthood: Type 1 cytochrome B5 reductase deficiency.Irish journal of medical science · 2026Review
- Pulse Oximetry-A Perioperative Perspective.Diagnostics (Basel, Switzerland) · 2026Review
- Article
- Carboxyhemoglobin tracks acute arterial desaturation in healthy volunteers: a pooled analysis of four controlled desaturation studies.Scientific reports · 2026Article
- Enhancing triapine treatment: strategies for dose optimization and methemoglobin level mitigation.Cancer chemotherapy and pharmacology · 2026Article
- Severe Methemoglobinemia Due to Accidental Ingestion of Nitrite-Containing Nail Polish Remover: A Case Report.The American journal of case reports · 2026Article
- Breath-by-breath quantification of inhaled nitric oxide absorption and modeling of methemoglobin kinetics.Redox biology · 2026Article
- Prevalence of methemoglobinemia after lidocaine as add-on therapy in neonatal seizures.European journal of pediatrics · 2026Article
- European Reference Networks - a flagship activity of the EU in the field of rare and complex diseases: from 2017 to 2025.Orphanet journal of rare diseases · 2026Review
- Severe methemoglobinemia resulting from intentional sodium hypochlorite poisoning in a 13-year-old girl hospitalized in the intensive care unit: a case report.Anaesthesiology intensive therapy · 2026Article
- Unveiling the Influence of the Graded Impact of Cigarette Smoking Intensity on the Biochemical and Morphological Alterations of Erythrocytes.Cell biochemistry and biophysics · 2026Article
46 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 17 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methemoglobinemia is a rare disorder associated with oxidization of divalent ferro-iron of hemoglobin (Hb) to ferri-iron of methemoglobin (MetHb). Methemoglobinemia can result from either inherited or acquired processes. Acquired forms are the most common, mainly due to the exposure to substances that cause oxidation of the Hb both directly or indirectly. Inherited forms are due either to autosomal recessive variants in the CYB5R3 gene or to autosomal dominant variants in the globin genes, collectively known as HbM disease. Our recommendations are based on a systematic literature search. A series of questions regarding the key signs and symptoms, the methods for diagnosis, the clinical management in neonatal/childhood/adulthood period, and the therapeutic approach of methemoglobinemia were formulated and the relative recommendations were produced. An agreement was obtained using a Delphi-like approach and the experts panel reached a final consensus >75% of agreement for all the questions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.