Evidence map›Paper›PMID 34467555›Full record

ArticleClinical oral implants research2021

Clinical and radiological outcomes of novel digital workflow and dynamic navigation for single-implant immediate loading in aesthetic zone: 1-year prospective case series.

Alessandro Pozzi, Lorenzo Arcuri, Paolo Carosi, Alessandra Nardi, Joseph Kan

Registry-linked trialAbstract read
In one paragraph

Article in Clinical oral implants research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05526677 (Effectiveness Evaluation of the Digital Workflow for Single-implant Immediate Loading), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05526677 unknown statusnot on this mapstarted 2022, after this paper: background citation

Effectiveness Evaluation of the Digital Workflow for Single-implant Immediate Loading

Typeobservational_patient_registrySponsorKaohsiung Medical University Chung-Ho Memorial HospitalRan2022 to 2025Enrolled60ConditionsSingle Missing Tooth RehabilitationArmsx-guide dynamic navigation system
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Beyond Accuracy: Clinical Outcomes of Computer Assisted Implant Surgery.Clinical and experimental dental research · 2025
    Review
  4. Article
  5. [Accuracy of dynamic navigation system for immediate dental implant placement].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alessandro PozziGoldstein Center for Esthetic and Implant Dentistry, Department of Restorative Sciences, Augusta University, Augusta, GA, USA.ORCID https://orcid.org/0000-0002-3052-8186
Lorenzo ArcuriDepartment of Chemical Science and Technologies, PhD in Materials for Health, Environment and Energy-Dentistry, University of Rome Tor Vergata, Rome, Italy.
Paolo CarosiDepartment of Chemical Science and Technologies, PhD in Materials for Health, Environment and Energy-Dentistry, University of Rome Tor Vergata, Rome, Italy.ORCID https://orcid.org/0000-0002-2442-1091
Alessandra NardiDepartment of Mathematics, University of Rome Tor Vergata, Rome, Italy.
Joseph KanDepartment of Implant Dentistry, Loma Linda University School of Dentistry, Loma Linda, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate clinical, radiological performance of novel digital workflow integrating dynamic navigation to streamline in one-visit single-implant immediate loading in aesthetic zone. MATERIAL AND

methodsConsecutive patients requiring one single-implant in aesthetic zone of both jaws were treated between May and September 2017. Primary outcomes were implant and prosthetic success rates, surgical and prosthetic complications, marginal bone loss (MBL), final pink aesthetic score (PES-f), and implant stability quotient (ISQ-f). Secondary outcomes were ISQ-0 and PES-0 at implant positioning and PES-p at definitive prosthesis placement. Potential effect of jaw (maxilla vs mandible), biotype (thin vs thick), type of incision (flap vs flapless), and implant site (healed vs. post-extractive) on the primary outcomes (MBL, PES-f, and ISQ-f) was evaluated through a multivariable analysis.

resultsFifty-two implants were placed (follow-up 18.6, 15-20 months). One post-extractive implant failed. No other surgical, biological complications occurred, accounting for 98.10% cumulative success rate (CSR). No definitive prostheses failed. Mean MBL was -0.63 ± 0.25 mm (-1.69 to -0.06). PES-f was 12.34 ± 1.41 (9-14). ISQ-f was 78.1 ± 3.2 (70-84). Age had significantly negative effect on MBL and PES-f (p = .0058 and p = .0052). No other variables significantly affected primary outcomes.

conclusionsWithin study limitations, investigated digital workflow integrating dynamic navigation was reliable for single-implant immediate loading in aesthetic zone in one visit. No statistically significant difference was found for MBL, PES-f, and ISQ-f, considering type of incision (flap vs. flapless), implant site (healed vs post-extractive), jaw (maxilla vs. mandible), and biotype (thick vs. thin). Live-tracked dynamic navigation may have contributed to improve operator clinical performance regardless of implant site characteristics. Further investigations are needed to confirm positive outcomes.

Indexed as

Dental ImplantsDental Implants, Single-ToothImmediate Dental Implant LoadingDental Prosthesis, Implant-SupportedEsthetics, DentalFollow-Up StudiesHumansMaxillaTreatment OutcomeWorkflowDental Implantsdental implantdigital workflowDynamic navigationguided surgeryimmediate loading

Identifiers

PMID34467555
PMCPMC9292693

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.