Evidence map›Paper›PMID 34467512›Full record

ArticleAnnals of biomedical engineering2021

Parametric Analysis of an Integrated Model of Cardio-respiratory Interactions in Adults in the Context of Obstructive Sleep Apnea.

Gustavo Guerrero, Virginie Le Rolle, Alfredo Hernández

Abstract read
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In one paragraph

Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gustavo GuerreroUniv Rennes, Inserm, LTSI - UMR 1099, Campus de Beaulieu, Bât 22, 35042, Rennes, France.
Virginie Le RolleUniv Rennes, Inserm, LTSI - UMR 1099, Campus de Beaulieu, Bât 22, 35042, Rennes, France. virginie.lerolle@univ-rennes1.fr.ORCID http://orcid.org/0000-0003-1068-5587
Alfredo HernándezUniv Rennes, Inserm, LTSI - UMR 1099, Campus de Beaulieu, Bât 22, 35042, Rennes, France.
Inserm · FR

Funding

Horizon 2020 Framework Programme 689260
6 · The paper itself

Abstract

An original integrated model of cardio-respiratory interactions is presented in this paper with the objective of studying the acute physiological responses evoked by obstructive sleep apnea events in adults. A comprehensive sensitivity analysis of the model is proposed during the simulation of a 20 s obstructive apnea episode using the Morris' screening method and local sensitivity analysis. The more relevant parameters are related to the following mechanisms of the physiology: (i) the fraction of oxygen in inspired air, (ii) metabolic rates (oxygen consumption rate, CO

Indexed as

Computer SimulationModels, CardiovascularAdultBlood CirculationHeart Conduction SystemHumansOxygen ConsumptionPulmonary Gas ExchangeRespiratory MechanicsSleep Apnea, ObstructiveCardiorespiratory modelIn silicoSensitivity analysisSleep disorders

Identifiers

PMID34467512
OpenAlexW3196844158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.