Evidence map›Paper›PMID 34467413›Full record

ArticleInternational journal of colorectal disease2021

Transanal (TaTME) vs. laparoscopic total mesorectal excision for mid and low rectal cancer: a propensity score-matched analysis of early and long-term outcomes.

Martino Munini, Sotirios Georgios Popeskou, Ken Galetti, Raffaello Roesel, Francesco Mongelli, Dimitri Christoforidis

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In one paragraph

Article in International journal of colorectal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 7 pooled it
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 7 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Martino Munini *Department of Surgery, Lugano Regional Hospital, via Tesserete 46, Lugano, 6900, Switzerland.ORCID http://orcid.org/0000-0003-0332-9357
Sotirios Georgios Popeskou *Department of Surgery, Lugano Regional Hospital, via Tesserete 46, Lugano, 6900, Switzerland.ORCID http://orcid.org/0000-0001-8971-5624
Ken GalettiDepartment of Surgery, Beata Vergine Hospital, Via Alfonso Turconi 23, Mendrisio, 6850, Switzerland.ORCID http://orcid.org/0000-0002-9037-991X
Raffaello RoeselDepartment of Surgery, Lugano Regional Hospital, via Tesserete 46, Lugano, 6900, Switzerland.ORCID http://orcid.org/0000-0002-1711-7622
Francesco MongelliDepartment of Surgery, Lugano Regional Hospital, via Tesserete 46, Lugano, 6900, Switzerland. francesco.mongelli@mail.com.ORCID http://orcid.org/0000-0002-8824-651X
Dimitri ChristoforidisDepartment of Surgery, Lugano Regional Hospital, via Tesserete 46, Lugano, 6900, Switzerland.ORCID http://orcid.org/0000-0002-8194-282X
Ospedale regionale di Lugano · CHOspedale Regionale di Mendrisio · CHUniversity Hospital of Lausanne · CHUniversity of Applied Sciences and Arts of Southern Switzerland · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTransanal total mesorectal excision (TaTME) has been proposed as an alternative to laparoscopic total mesorectal excision (LapTME) in distal rectal tumors. Despite encouraging reports, mid- and long-term oncological results are limited. In this study, we aimed at comparing TaTME versus LapTME in patients with mid and low rectal cancer.

methodsFrom January 2012 to December 2019, all patients undergoing either TaTME or LapTME for rectal adenocarcinoma ≤ 12 cm from the anal verge were included. Demographic, clinical, and follow-up data were retrieved from a prospective and audited database, and a propensity score-matched analysis was performed.

resultsA total of 144 patients were included, 38 underwent TaTME, and 106 LapTME. The median age was 68.0 (60.2-75.8) years, and 96 (66.7%) patients were male. Median follow-up was 30.6 (20.2-39.8) months in the TaTME group and 49.5 (22.6-68.5) months in the LapTME group. There was one (2.6%) local recurrence in the TaTME group and two (1.9%) in the LapTME group (p = 0.788). There was no difference in the 3-year disease-free survival between groups both in the primary (93% vs. 86%, p = 0.274) and the propensity score-matched analyses (93% vs. 81%, p = 0.132). Conversion to open surgery was less frequent in the TaTME group (none vs. 4 (11.4%), p = 0.041). Intra- and postoperative complications, length of stay, specimen quality, and resection margins were similar between groups.

conclusionsIn our experience, TaTME was associated with a less frequent conversion to open surgery but otherwise had similar post-operative results compared to LapTME. Local recurrence and 3-year survival rates were similar.

Indexed as

LaparoscopyRectal NeoplasmsTransanal Endoscopic SurgeryAgedHumansMaleNeoplasm Recurrence, LocalPostoperative ComplicationsPropensity ScoreProspective StudiesRectumTreatment OutcomeDisease-free survivalRectal cancerTaTMETotal mesorectal excisionTransanal surgery

Identifiers

PMID34467413
OpenAlexW3197931481

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.