ArticleCell reports. Medicine2021
Molecular analysis of the 2012 Bundibugyo virus disease outbreak.
Article in Cell reports. Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 7 citations in OpenAlex.
- Underinvestment in diagnostic and vaccine research & development has put the world at greater risk from the Bundibugyo virus epidemic in 2026.Virulence · 2026Article
- Bundibugyo virus disease and the unfinished countermeasure agenda.Bulletin of the World Health Organization · 2026Article
- A generalized multi-population model for Ebola virus transmission incorporating environmental reservoir dynamics.Infectious medicine · 2026Article
- Ebola Bundibugyo resurgence in eastern Democratic Republic of Congo: Implications for regional surveillance and preparedness.Journal of virus eradication · 2026Article
- Review
- On the 50th year responding to Ebola: mapping diagnostic, vaccine, and therapeutic gaps across ebolavirus species.MedScience · 2026Review
- Clinical profile and genomic characterization of the 2026 Bundibugyo virus index case in Uganda.Nature medicine · 2026Article
- Bundibugyo Virus Disease: Diagnostics and Medical Countermeasures for a Neglected Ebolavirus.Viruses · 2026Review
- Mapping the global evidence base of bundibugyo ebolavirus disease: a systematic scoping review of research gaps and preparedness priorities.BMC infectious diseases · 2026Article
- Closing Critical Gaps in the 2026 Bundibugyo Ebola Response: Five Actionable Priorities.Cureus · 2026Article
- Review
- 2026 Bundibugyo virus outbreak: the role of genomics inMicrobial genomics · 2026Article
- The Re-Emergence of Bundibugyo Ebolavirus in Uganda and the Democratic Republic of Congo: Epidemiological Drivers, Response Strategies, and Implications for Global Health Security.Infection and drug resistance · 2026Review
- Review
- The Multiple Origins of Ebola Disease Outbreaks.The Journal of infectious diseases · 2023Review
- Epidemiology of Ebolaviruses from an Etiological Perspective.Pathogens (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
17 authors at 3 institutions in 2 countries.
Funding
Abstract
Bundibugyo virus (BDBV) is one of four ebolaviruses known to cause disease in humans. Bundibugyo virus disease (BVD) outbreaks occurred in 2007-2008 in Bundibugyo District, Uganda, and in 2012 in Isiro, Province Orientale, Democratic Republic of the Congo. The 2012 BVD outbreak resulted in 38 laboratory-confirmed cases of human infection, 13 of whom died. However, only 4 BDBV specimens from the 2012 outbreak have been sequenced. Here, we provide BDBV sequences from seven additional patients. Analysis of the molecular epidemiology and evolutionary dynamics of the 2012 outbreak with these additional isolates challenges the current hypothesis that the outbreak was the result of a single spillover event. In addition, one patient record indicates that BDBV's initial emergence in Isiro occurred 50 days earlier than previously accepted. Collectively, this work demonstrates how retrospective sequencing can be used to elucidate outbreak origins and provide epidemiological contexts to a medically relevant pathogen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.