Evidence map›Paper›PMID 34466590›Full record

ArticleGalen medical journal2020

A Life-Changing Moment in a Patient with Type 1 Diabetes: Insulin Holiday.

Muhammad Imran Butt, Noha Mukhtar, Muhammad Riazuddin, Lama Amer, Tarek Elsayed

Abstract readCase Reports
In one paragraph

Article in Galen medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad Imran ButtKing Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Noha MukhtarKing Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Muhammad RiazuddinKing Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Lama AmerKing Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.
Tarek ElsayedKing Faisal Specialist Hospital & Research Centre, Riyadh, Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnosis of type 1 diabetes can be a life-changing moment for our patients particularly having to live with the idea of taking insulin all their life and the barriers it can bring about. CASE REPORT: We report a patient with ten years of autoimmune type 1 diabetes treated with insulin. He was able to stop insulin in favour of oral diabetes agents after dynamic endocrine tests confirmed micro insulin secretion despite autoimmunity. Our case demonstrates that a detailed history and thorough investigations adopting a holistic approach can sometimes change the course of disease management and can leave a positive impact on the life of our patients.

conclusionPatients with partial retention of beta-cell function in type 1 diabetes can temporarily stop insulin safely with ongoing surveillance.

Indexed as

Autoimmune DiabetesAutoimmunityDiabetic KetoacidosisInsulin SecretionIslets of LangerhansType 1 Diabetes

Identifiers

PMID34466590
PMCPMC8344034

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.