Evidence map›Paper›PMID 34466580›Full record

ArticleGalen medical journal2020

Narges Jamshidian Tehrani, Zahra Amirghofran, Ali Reza Shamsaeefar, Aida Karachi, Mohammad Hossein Karimi

Open access · diamondAbstract read
In one paragraph

Article in Galen medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Narges Jamshidian TehraniOrgan Transplant Research Center, Shiraz University of Medical Science, Shiraz, Iran.
Zahra AmirghofranShiraz University of Medical Science, Shiraz, Iran.
Ali Reza ShamsaeefarOrgan Transplant Research Center, Shiraz University of Medical Science, Shiraz, Iran.
Aida KarachiOrgan Transplant Research Center, Shiraz University of Medical Science, Shiraz, Iran.
Mohammad Hossein KarimiOrgan Transplant Research Center, Shiraz University of Medical Science, Shiraz, Iran.
Shiraz University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been well-documented that the Fc receptor-like (FCRL) molecule contributes to the pathogenesis of certain autoimmune disorders. FCRL molecules belong to the immunoglobulin superfamily produced by B cells. Also, these molecules induce activating or inhibitory signals of B cells. According to this information and also considering the critical role of immune reactions in organ transplantation, the following experiment was performed to analyze the gene expression level of MATERIALS AND

methodsBlood samples were obtained from 32 renal transplant patients on days 1, 3, and 7 post-transplantations. Patients were divided into two groups according to the presence or absence of rejection. Also, 24 age-matched healthy subjects were enrolled as control group. After total RNA extraction from peripheral blood mononuclear cells (PBMC) and cDNA synthesis, the gene expression levels of

resultsOur results showed that

conclusionIt can be concluded that mononuclear cells, mainly B cells, have an essential role to play in kidney transplantation.

Indexed as

Fc Receptor-Like MoleculesKidney TransplantationPeripheral Blood Mononuclear Cells

Identifiers

PMID34466580
PMCPMC8343822
OpenAlexW3084803394

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.