ArticleGalen medical journal2019
Breast Cancer Interaction Network Concept from Mostly Related Components.
Article in Galen medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Coherent pathway enrichment estimation by modeling inter-pathway dependencies using regularized regression.Bioinformatics (Oxford, England) · 2023Article
- Highlighted role of "IL17 signaling pathway" in gastroesophageal reflux disease.Gastroenterology and hepatology from bed to bench · 2020Article
- Radiation Therapy in Patients With Brain Cancer: Post-proteomics Interpretation.Journal of lasers in medical sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundManagement of breast cancer (BC) as a heterogeneous disease is very challenging. Biomarker discovery has been shown promising for this aim. Protein interaction mapping could provide further knowledge of the vital roles of these markers. MATERIALS AND
methodsCytoscape and its plug-ins are used for network construction and evaluation. The plug-ins used in this study are STRING, Network Analyzer, GeneMANIA, and CluePedia.
resultsThe central proteins are enriched in transcription regulatory region DNA binding, regulatory region nucleic acid binding, regulatory region DNA binding, Fc receptor signaling pathway, cell cycle arrest, and immune response-regulating cell surface receptor signaling pathway.
conclusionThe introduced biomarkers and their related biological processes may show useful for the breast cancer diagnosis and monitoring; however, has to encounter more validation studies to be clinically applicable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.