Evidence map›Paper›PMID 34466471›Full record

ArticleGalen medical journal2019

Effects of Olive Leaf Extract on Prevention of Molecular, Histopathological, and Enzymatic Changes in Chicken Carbon Tetrachloride-Induced Liver Damage.

Nazila Vahidi-Eyrisofla, Vida Hojati, Mohammad-Reza Yazdian, Morteza Zendehdel, Hooman Shajiee

Open access · hybridAbstract read
In one paragraph

Article in Galen medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Hepatoprotective Effects ofAnimals : an open access journal from MDPI · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nazila Vahidi-EyrisoflaDepartment of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Vida HojatiDepartment of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Mohammad-Reza YazdianDepartment of Medical Science, Qom Branch, Islamic Azad University, Qom, Iran.
Morteza ZendehdelDepartment of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Hooman ShajieeDepartment of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Islamic Azad University, Damghan Branch · IRQom Islamic Azad University · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundToday, the use of additives such as antibiotics and growth hormones that increase production efficiency in breeding broiler chickens has become inevitable. However, the use of such additives and antibiotics associated with side effects such as liver damage. Oxidative stress occurs due to an imbalance between oxidants and antioxidants. Studies have shown that olive leaves have an antioxidant effect on free radicals. This study was to evaluate the possible effect of olive leaf extract on carbon tetrachloride (CCL4)-induced liver damage (molecular and tissue) and changes of enzymes in chickens. MATERIALS AND

methodsA total of 50 chickens were used and classified into5 groups. Treatment groups received 0.5, 1, and 1.5 mg/kg of the olive leaf extract from day 21 of the experiment. Two control groups-healthy and poisoned-did not receive any extract. On the day 35 of the experiment, 1cc of CCL4 was dissolved with olive oil and injected intraperitoneally into the experimental and poisoned control groups. Blood and liver tissue sampling were performed.

resultsThe histopathology results showed that at high doses of olive leaf extract, the cells and vessels were regularly curable, and sinusoids were healthy. The expression of B-cell lymphoma 2 (

conclusionWe concluded that olive leaf extract boosts the

Indexed as

Carbon TetrachlorideChickenLiverOlive

Identifiers

PMID34466471
PMCPMC8343934
OpenAlexW2959360971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.