Evidence map›Paper›PMID 34466380›Full record

ArticlePhotoacoustics2021

A backward-mode optical-resolution photoacoustic microscope for 3D imaging using a planar Fabry-Pérot sensor.

Elisabeth Baumann, Ulrike Pohle, Edward Zhang, Thomas Allen, Claus Villringer, Silvio Pulwer, Holger Gerhardt, Jan Laufer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Photoacoustics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisabeth BaumannIntegrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125, Berlin, Germany.
Ulrike PohleInstitut für Physik, Martin-Luther-Universität Halle-Wittenberg, Von-danckelmann-platz 3, 06120, Halle (Saale), Germany.
Edward ZhangDepartment of Medical Physics and Biomedical Engineering, University College London, Gower Street, WC1E 6BT, UK.
Thomas AllenDepartment of Medical Physics and Biomedical Engineering, University College London, Gower Street, WC1E 6BT, UK.
Claus VillringerInstitut für Physik, Martin-Luther-Universität Halle-Wittenberg, Von-danckelmann-platz 3, 06120, Halle (Saale), Germany.
Silvio PulwerUniversity of Applied Sciences Wildau, Hochschulring 1, 15745, Wildau, Germany.
Holger GerhardtIntegrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125, Berlin, Germany.
Jan LauferInstitut für Physik, Martin-Luther-Universität Halle-Wittenberg, Von-danckelmann-platz 3, 06120, Halle (Saale), Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical-resolution photoacoustic microscopy (OR-PAM) combines high spatial resolution and strong absorption-based contrast in tissue, which has enabled structural and spectroscopic imaging of endogenous chromophores, primarily hemoglobin. Conventional piezoelectric ultrasound transducers are typically placed far away from the photoacoustic source due to their opacity, which reduces acoustic sensitivity. Optical ultrasound sensors are an alternative as their transparency allows them to be positioned close to the sample with minimal source-detector distances. In this work, a backward-mode OR-PAM system based on a planar Fabry-Pérot ultrasound sensor and coaxially aligned excitation and interrogation beams was developed. Two 3D imaging modes, using raster-scanning for enhanced image quality and continuous-scanning for fast imaging, were implemented and tested on a leaf skeleton phantom. In fast imaging mode, a scan-rate of 100,000 A-lines/s was achieved. 3D images of a zebrafish embryo were acquired

Indexed as

Backward-mode imagingContinuous scanningDual-wavelengthIn vivo imagingOptical-resolution photoacoustic microscopyOptical ultrasound sensingPlanar Fabry-Pérot interferometer

Identifiers

PMID34466380
PMCPMC8385441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.