Evidence map›Paper›PMID 34466092›Full record

ReviewSaudi journal of biological sciences2021

Using essential oils to overcome bacterial biofilm formation and their antimicrobial resistance.

Khaled A El-Tarabily, Mohamed T El-Saadony, Mahmoud Alagawany, Muhammad Arif, Gaber E Batiha, Asmaa F Khafaga, Hamada A M Elwan, Shaaban S Elnesr, Mohamed E Abd El-Hack

Abstract readReview
In one paragraph

Review in Saudi journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Comparative Evaluation of 3 Commercial Mouthwash Formulations on Clinical Parameters of Chronic Gingivitis.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Trial
  3. Article
  4. Review
  5. Article
  6. Essential Oil Derived from Horticultural By-Products ofMolecules (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. South Tyrol (Italy)Molecules (Basel, Switzerland) · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Effective killing ofMicrobiology spectrum · 2025
    Article
  19. Antimicrobial efficacy and cytotoxicity of ethanolic extracts ofJournal of advanced periodontology & implant dentistry · 2025
    Article
  20. Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Khaled A El-TarabilyDepartment of Biology, College of Science, United Arab Emirates University, 15551 Al-Ain, United Arab Emirates.
Mohamed T El-SaadonyDepartment of Agricultural Microbiology, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.
Mahmoud AlagawanyDepartment of Poultry, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.
Muhammad ArifDepartment of Animal Sciences, College of Agriculture, University of Sargodha, Sargodha, Pakistan.
Gaber E BatihaNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, 080-8555 Obihiro, Hokkaido, Japan.
Asmaa F KhafagaDepartment of Pathology, Faculty of Veterinary Medicine, Alexandria University, Edfina 22758, Egypt.
Hamada A M ElwanDepartment of Animal and Poultry Production, Faculty of Agriculture, Minia University, El-Minya 61519, Egypt.
Shaaban S ElnesrDepartment of Poultry Production, Faculty of Agriculture, Fayoum University, Fayoum 63514, Egypt.
Mohamed E Abd El-HackDepartment of Poultry, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase of resistant bacteria puts a huge pressure on the antimicrobials in current use. Antimicrobial resistance (AMR) results from antibiotic misuse and abuse over many years and is a global financial burden. New polices must be developed for the use of antimicrobials and to continue research efforts to mitigate AMR. It is essential to target the most harmful bacteria and concentrate on their mechanisms of resistance to develop successful antimicrobials. Essential oils (EOs) are occur naturally in plants and have long been used as antimicrobials, but most have not been researched. This review explores EOs as alternative antimicrobials, investigating their ability to decrease or inhibit biofilm formation, and assess their ability to contribute to AMR control. Low concentrations of EOs can inhibit Gram-positive and Gram-negative pathogenic bacteria. Some EOs have demonstrated strong anti-biofilm activities. If EOs are successful against biofilm formation, particularly in bacteria developing AMR, they could be incorporated into new antimicrobials. Therefore, there is a need to investigate these EOs' potential, particularly for surface disinfection, and against bacteria from food, clinical and non-clinical environments.

Indexed as

Antimicrobial resistanceBiofilm toleranceEssential oilsHealth

Identifiers

PMID34466092
PMCPMC8380992

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.