Evidence map›Paper›PMID 34466072›Full record

ArticleSaudi journal of biological sciences2021

Chemical composition and pharmacological bio-efficacy of

Saima Ali, Muhammad Rashid Khan, Javed Iqbal, Riffat Batool, Irum Naz, Tabassum Yaseen, Banzeer Ahsan Abbasi, Jamal Abdul Nasir, Hamed A El-Serehy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Antioxidant, Anticancer, and PXR-Dependent CYPOxidative medicine and cellular longevity · 2022
    Article
  5. Chemical composition ofSaudi journal of biological sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Saima AliDepartment of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Muhammad Rashid KhanDepartment of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Javed IqbalDepartment of Botany, Bacha Khan University, Charsadda, Khyber Pakhtunkkhwa, Pakistan.
Riffat BatoolDepartment of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Irum NazDepartment of Biochemistry, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Tabassum YaseenDepartment of Botany, Bacha Khan University, Charsadda, Khyber Pakhtunkkhwa, Pakistan.
Banzeer Ahsan AbbasiDepartment of Plant Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Jamal Abdul NasirUniversity College London, Kathleen Lonsdale Materials Chemistry, Department of Chemistry, 20 Gordon Street, London WC1H 0AJ, UK.
Hamed A El-SerehyDepartment of Zoology, College of Science, King Saud University, Riyadh l1451, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consistent STAT3 (Single transducer and activator of transcription 3) activation is observed in many tumors and promotes malignant cell transformation. In the present investigation, we evaluated the anticancer effects of

Indexed as

ApoptosisBAK, Bcl-2 homologous antagonist/killerBAX, Bcl-2-Associate X proteinBCL-XL, B-cell lymphoma-extra largeCancerHCCLM3JAK-1/2, Janus kinase-1/2MDA–MB 231MMP-2/9, Matrix metalloproteinases-2/9MTT, 3-(4, 5-Dimethylthiazol-2-yl) −2,5 diphenyltetrazoliumbromidePARP, Poly (ADP-ribose) polymeraseParrotiopsis jacquemontianaPIAS-1/3, Protein Inhibitor of Activated STATs-1/3SHP-1/2, Src-homology region 2 domain-containing phosphatase-1/2STAT3STAT3, Single transducer and activator of transcription 3StatticXIAP, X-linked inhibitor of apoptosis protein

Identifiers

PMID34466072
PMCPMC8381063

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.