Evidence map›Paper›PMID 34466045›Full record

ArticleNature and science of sleep2021

Artificial Intelligence Analysis of Mandibular Movements Enables Accurate Detection of Phasic Sleep Bruxism in OSA Patients: A Pilot Study.

Jean-Benoit Martinot, Nhat-Nam Le-Dong, Valérie Cuthbert, Stéphane Denison, David Gozal, Gilles Lavigne, Jean-Louis Pépin

Open access · goldAbstract read
In one paragraph

Article in Nature and science of sleep, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
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  5. Article
  6. Review
  7. Review
  8. Review
  9. Insights on mandibular jaw movements during polysomnography in obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  10. Review
  11. Article
  12. Diagnostic accuracy of ambulatory polysomnography with electroencephalogram for detection of sleep bruxism-related masticatory muscle activity.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Jean-Benoit MartinotSleep Laboratory, CHU Université Catholique de Louvain (UCL) Namur Site Sainte-Elisabeth, Namur, 5000, Belgium.ORCID 0000-0001-8536-7300
Nhat-Nam Le-DongSunrise, Namur, 5101, Belgium.
Valérie CuthbertSleep Laboratory, CHU Université Catholique de Louvain (UCL) Namur Site Sainte-Elisabeth, Namur, 5000, Belgium.
Stéphane DenisonSunrise, Namur, 5101, Belgium.
David GozalDepartment of Child Health and Child Health Research Institute, University of Missouri, Columbia, MO, 65201, USA.
Gilles LavigneFaculté de médecine dentaire, Université de Montréal, Montréal, Québec, H3C 3J7, Canada.
Jean-Louis PépinHP2 Laboratory, Inserm U1042, University Grenoble Alpes, Grenoble, 38000, France.ORCID 0000-0003-3832-2358
UCLouvain · BEInserm · FRUniversité de Montréal · CAUniversity of Missouri Health System · US

Funding

APP-mediated signaling, sleep perturbations, and Alzheimer's disease mouse modelsRF1AG061824 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI GOZAL, DAVID, PARENT, ANGELE · 2019 to 2019
$3.5M
HL - Exosomes, Blood, Brain Barrier, and Cognitive Function in Pediatric OSAR01HL130984 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI GOZAL, LEILA KHEIRANDISH · 2016 to 2020
$3.5M
Plasma Exosomes and Vascular Dysfunction in Adults with Sleep ApneaR56HL140548 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI GOZAL, DAVID · 2018 to 2018
$794k
NHLBI NIH HHS R01 HL130984NHLBI NIH HHS R56 HL140548NIA NIH HHS RF1 AG061824
6 · The paper itself

Abstract

purposeSleep bruxism (SBx) activity is classically identified by capturing masseter and/or temporalis masticatory muscles electromyographic activity (EMG-MMA) during in-laboratory polysomnography (PSG). We aimed to identify stereotypical mandibular jaw movements (MJM) in patients with SBx and to develop rhythmic masticatory muscles activities (RMMA) automatic detection using an artificial intelligence (AI) based approach. PATIENTS AND

methodsThis was a prospective, observational study of 67 suspected obstructive sleep apnea (OSA) patients in whom PSG with masseter EMG was performed with simultaneous MJM recordings. The system used to collect MJM consisted of a small hardware device attached on the chin that communicates to a cloud-based infrastructure. An extreme gradient boosting (XGB) multiclass classifier was trained on 79,650 10-second epochs of MJM data from the 39 subjects with a history of SBx targeting 3 labels: RMMA episodes (n=1072), micro-arousals (n=1311), and MJM occurring at the breathing frequency (n=77,267).

resultsValidated on unseen data from 28 patients, the model showed a very good epoch-by-epoch agreement (Kappa = 0.799) and balanced accuracy of 86.6% was found for the MJM events when using RMMA standards. The RMMA episodes were detected with a sensitivity of 84.3%. Class-wise receiver operating characteristic (ROC) curve analysis confirmed the well-balanced performance of the classifier for RMMA (ROC area under the curve: 0.98, 95% confidence interval [CI] 0.97-0.99). There was good agreement between the MJM analytic model and manual EMG signal scoring of RMMA (median bias -0.80 events/h, 95% CI -9.77 to 2.85).

conclusionSBx can be reliably identified, quantified, and characterized with MJM when subjected to automated analysis supported by AI technology.

Indexed as

jaw movementmachine learningmasticatory muscular activities

Identifiers

PMID34466045
PMCPMC8397703
OpenAlexW3193668782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.