Evidence map›Paper›PMID 34466037›Full record

ArticleInternational medical case reports journal2021

High Dose Cabergoline in Management of Bilateral Ovarian Hyperstimulation Syndrome: A Case Report.

Gulparkha Manalai, Asadullah Shirzai, Ahmad Khalid Aalemi

Abstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gulparkha ManalaiDepartment of Obstetrics and Gynecology, Shahrara Teaching Hospital, Kabul University of Medical Sciences, Kabul, Afghanistan.
Asadullah ShirzaiDepartment of Medical Imaging and Radiation Sciences, Kabul University of Medical Sciences, Kabul, Afghanistan.
Ahmad Khalid AalemiDepartment of Epidemiology, Kabul University of Medical Sciences, Kabul, Afghanistan.ORCID 0000-0003-0111-634X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian hyperstimulation syndrome (OHSS) is an exaggerated response to excess hormones and is also one of the life-threatening iatrogenic complications which is associated with ovulation induction. This syndrome usually occurs in women who receive injectable hormones for the stimulation of egg development in the ovaries. This study describes a rare case of moderate ovarian hyperstimulation syndrome which has been managed and treated with high-dose cabergoline. The patient was diagnosed in the Medical Imaging and Radiation Sciences Department of Kabul University of Medical Sciences and treated in Shahrara Teaching Hospital. A 26-year-old woman was diagnosed with the development of bilateral moderate ovarian hyperstimulation syndrome after receiving clomiphene citrate in dose of 100 mg BID on day 5 of period and Human Chorionic Gonadotropin (HCG) 10,000 units for egg release on day 14 of period. The patient was given a high dose of cabergoline. The dose was adjusted to 1 mg/day for eight days since she was diagnosed with ovarian hyperstimulation syndrome. Consequently, the main outcome of our intervention was complete resolution of OHSS as well as complete recovery of the patient. As a result, it is concluded that the high dose of cabergoline prevents and reduces the occurrence, prolongation, and severity of ovarian hyperstimulation syndrome. However, more assessments through randomized controlled trials regarding the efficacy and safety of cabergoline doses and treatment duration for treatment and preventive purposes are required.

Indexed as

assisted reproduction treatmentcabergolineovarian hyperstimulation syndrome

Identifiers

PMID34466037
PMCPMC8403006

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