ArticleNeuropsychiatric disease and treatment2021
Power Spectral Changes of Quantitative EEG in the Subjective Cognitive Decline: Comparison of Community Normal Control Groups.
Article in Neuropsychiatric disease and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Electroencephalography in Subjective Cognitive Decline and Mild Cognitive Impairment: Systematic Review of Biomarkers, Classification, and Prognostic Evidence.Journal of medical Internet research · 2026Pooled it
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- Source-space EEG alpha activity reveals brain age gaps due to neurodegeneration and disparity.Communications biology · 2026Article
- Theta Cordance Decline in Frontal and Temporal Cortices: Longitudinal Evidence of Regional Cortical Aging.Journal of clinical medicine · 2025Article
- Therapeutic Potential of Porcine Brain-Derived Peptide Mixture (PBDP) in Alzheimer's Disease: An Exploratory Study on Quantitative Electroencephalography (qEEG) Changes.Neuropsychiatric disease and treatment · 2025Article
- Brain Punch: K-1 Fights Affect Brain Wave Activity in Professional Kickboxers.Sports medicine (Auckland, N.Z.) · 2024Article
- Structural inequality and temporal brain dynamics across diverse samples.Clinical and translational medicine · 2024Article
- Disrupted brain functional connectivity as early signature in cognitively healthy individuals with pathological CSF amyloid/tau.Communications biology · 2024Article
- Brain health in diverse settings: How age, demographics and cognition shape brain function.NeuroImage · 2024Article
- PRedicting the EVolution of SubjectIvE Cognitive Decline to Alzheimer's Disease With machine learning: the PREVIEW study protocol.BMC neurology · 2023Article
- Neuronal Hyperactivation in EEG Data during Cognitive Tasks Is Related to the Apolipoprotein J/Clusterin Genotype in Nondemented Adults.International journal of molecular sciences · 2023Article
- qEEG as Biomarker for Alzheimer's Disease: Investigating Relative PSD Difference and Coherence Analysis.Neuropsychiatric disease and treatment · 2023Article
- Electroencephalography and mild cognitive impairment research: A scoping review and bibliometric analysis (ScoRBA).AIMS neuroscience · 2023Article
- Degradation of EEG microstates patterns in subjective cognitive decline and mild cognitive impairment: Early biomarkers along the Alzheimer's Disease continuum?NeuroImage. Clinical · 2023Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study is to compare and analyze the power spectral changes between subjective cognitive decline (SCD) subjects and normal controls (NC) while checking the preclinical stage of AD in the SCD subjects and to use the derived data for biomarker research that can diagnose early-stage AD in the future.
methodsWe recruited 23 SCD patients and 23 normal control subjects and QEEG analysis including power spectral density (PSD) and source-level analysis were performed. An automated preprocessing procedure and statistical analysis were performed by iSync Brain
resultsAbsolute PSD, there was no statistically significant difference in all of the EEG power measurements of the 19 channels. In the relative PSD analysis, the average delta band power of the SCD group was significantly higher in Fp2, F4, and F8 than NC. Alpha1 band power of the O1 channel was 22.56±16.05 for the SCD group and 33.19±19.05 for the NC (p-value <0.05). Source-level analysis did not show a statistically significant difference.
conclusionSCD subjects showed a partial increase of delta waves in the frontal lobe region and a partial decrease in alpha1, a fast wave in the occipital region, compared to the NC. SCD is considered one of the earliest clinical symptoms of AD and it is predicted to be related to minor nerve damage. We were able to observe the power spectral changes in SCD subjects in this cross-sectional study, a large number of subjects and longitudinal studies are needed to evaluate their predictability for future deterioration such as conversion to MCI.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.