ArticleNature neuroscience2021
Inferences on a multidimensional social hierarchy use a grid-like code.
Article in Nature neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05746299 (The Emergence of Abstract Structure Knowledge Across Learning and Sleep), which is not on this map. Cited by 82 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Emergence of Abstract Structure Knowledge Across Learning and Sleep
Who cites it
82 citing papers in PubMed, 200 citations in OpenAlex.
- The emergence of egocentric biases when comparing others is independent of whether groups or individuals are being compared.Royal Society open science · 2026Article
- Human brain-wide activation of sleep rhythms.eLife · 2026Article
- An abstract relational map emerges in the human medial prefrontal cortex with consolidation.Current biology : CB · 2026Article
- Antagonism shapes social maps in the human brain.Communications psychology · 2026Article
- Human hippocampal ripples coordinate planning sequences and compositional representations in neocortex.Nature neuroscience · 2026Article
- Latent neural architecture organising shared aesthetic evaluations of visual artworks.Nature communications · 2026Article
- Article
- Computational origins of cortical brain circuits for social cognition.Nature reviews. Neuroscience · 2026Review
- Medial temporal lobe encodes cognitive maps of real-world social networks.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Memory reactivation during sleep promotes structure abstraction.bioRxiv : the preprint server for biology · 2026Article
- Action information is integrated into entorhinal representations of conceptual space and is reflected in eye movements.PLoS biology · 2026Article
- Dynamic modeling in neurocognitive frameworks of childhood ADHD: a review of inhibitory control and reward systems.Translational psychiatry · 2026Review
- Lost in Space and Thought: Navigating the Cognitive Map in Alzheimer's Disease.Neuroscience bulletin · 2026Review
- Activity in human dorsal raphe nucleus signals changes in behavioural policy.Nature communications · 2026Article
- Map-like representations of emotion knowledge in hippocampal-prefrontal systems.Nature communications · 2026Article
- Neural sampling from cognitive maps enables goal-directed imagination and planning.Nature machine intelligence · 2026Article
- Neural traces of composite tasks in complex task representation in the human brain reflects learning performance.PLoS biology · 2026Article
- Cognitive Maps in the Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Graph-like organization of non-spatial knowledge about social closeness in movie narratives.Scientific reports · 2025Article
- Fragmentation and multithreading of experience in the default-mode network.Nature communications · 2025Article
22 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Generalizing experiences to guide decision-making in novel situations is a hallmark of flexible behavior. Cognitive maps of an environment or task can theoretically afford such flexibility, but direct evidence has proven elusive. In this study, we found that discretely sampled abstract relationships between entities in an unseen two-dimensional social hierarchy are reconstructed into a unitary two-dimensional cognitive map in the hippocampus and entorhinal cortex. We further show that humans use a grid-like code in entorhinal cortex and medial prefrontal cortex for inferred direct trajectories between entities in the reconstructed abstract space during discrete decisions. These grid-like representations in the entorhinal cortex are associated with decision value computations in the medial prefrontal cortex and temporoparietal junction. Collectively, these findings show that grid-like representations are used by the human brain to infer novel solutions, even in abstract and discrete problems, and suggest a general mechanism underpinning flexible decision-making and generalization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.