Evidence map›Paper›PMID 34465826›Full record

ArticleScientific reports2021

Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie.

Belén Marín, Alicia Otero, Séverine Lugan, Juan Carlos Espinosa, Alba Marín-Moreno, Enric Vidal, Carlos Hedman, Antonio Romero, Martí Pumarola, Juan J Badiola and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Classical BSE emergence from Nor98/atypical scrapie: Unraveling the shift vs. selection dichotomy in the prion field.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Belén Marín *Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Universidad de Zaragoza IA2 IIS Aragón, C/ Miguel Servet 177, 50013, Zaragoza, Spain.
Alicia Otero *Centro de Encefalopatías y Enfermedades Transmisibles Emergentes, Universidad de Zaragoza IA2 IIS Aragón, C/ Miguel Servet 177, 50013, Zaragoza, Spain. aliciaogar@unizar.es.
Séverine LuganUMR Institut National de La Recherche Agronomique (INRA)/École Nationale Vétérinaire de Toulouse (ENVT) 1225, Interactions Hôtes Agents Pathogènes, 31076, Toulouse, France.
Juan Carlos EspinosaCentro de Investigación en Sanidad Animal (CISA-INIA), 28130, Valdeolmos, Madrid, Spain.
Alba Marín-MorenoCentro de Investigación en Sanidad Animal (CISA-INIA), 28130, Valdeolmos, Madrid, Spain.
Enric VidalCentre de Recerca en Sanitat Animal, Universitat Autònoma de Barcelona (UAB)-Institut de Recerca i Tecnologia Agroalimentàries, 08193, Bellaterra, Barcelona, Spain.
Carlos HedmanCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Universidad de Zaragoza IA2 IIS Aragón, C/ Miguel Servet 177, 50013, Zaragoza, Spain.
Antonio RomeroServicio de Cirugía y Medicina Equina, Hospital Veterinario, Universidad de Zaragoza, 50013, Zaragoza, Spain.
Martí PumarolaDepartament de Medicina i Cirurgia Animals, Facultad de Veterinaria, Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Spain.
Juan J BadiolaCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Universidad de Zaragoza IA2 IIS Aragón, C/ Miguel Servet 177, 50013, Zaragoza, Spain.
Juan María TorresCentro de Investigación en Sanidad Animal (CISA-INIA), 28130, Valdeolmos, Madrid, Spain.
Olivier AndréolettiUMR Institut National de La Recherche Agronomique (INRA)/École Nationale Vétérinaire de Toulouse (ENVT) 1225, Interactions Hôtes Agents Pathogènes, 31076, Toulouse, France.
Rosa BoleaCentro de Encefalopatías y Enfermedades Transmisibles Emergentes, Universidad de Zaragoza IA2 IIS Aragón, C/ Miguel Servet 177, 50013, Zaragoza, Spain.
Universidad de Zaragoza · ESDépartement Santé Animale · FRInstituto de Investigación Sanitaria Aragón · ESUniversitat Autònoma de Barcelona · ESCentro de Investigación en Sanidad AnimalÉcole Nationale Vétérinaire de Toulouse · FRInstitut National Polytechnique de Toulouse · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrP

Indexed as

Disease SusceptibilityAnimalsBrainCattleEncephalopathy, Bovine SpongiformFemaleMaleMicePrionsPrPSc ProteinsScrapieSwineSwine, MiniaturePrionsPrPSc Proteins

Identifiers

PMID34465826
PMCPMC8408226
OpenAlexW3198785565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.