Evidence map›Paper›PMID 34465804›Full record

ArticleScientific reports2021

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Patrick M Siegel, Laura Sander, Alba Fricke, Johannes Stamm, Xiaowei Wang, Prerna Sharma, Nicole Bassler, Ya-Lan Ying, Christoph B Olivier, Steffen U Eisenhardt and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Serum metabolomics identifies biomarkers in radicular cysts.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  5. Monocytes/Macrophages and Atherogenesis.International journal of molecular sciences · 2025
    Review
  6. Integrated Stress Response Signatures Drive Monocyte Dysfunction inmedRxiv : the preprint server for health sciences · 2025
    Article
  7. Review
  8. Article
  9. The Signaling Pathway of the ADP Receptor P2YInternational journal of molecular sciences · 2023
    Review
  10. Article
  11. Bindarit encapsulated nanoparticles prevent venous neointimal hyperplasia and restenosis in a murine angioplasty model.Translational research : the journal of laboratory and clinical medicine · 2022
    Article
  12. Article
  13. P2YFrontiers in cardiovascular medicine · 2022
    Review
  14. P2YCells · 2021
    Article
  15. Combined Antiplatelet Therapy Reduces the Proinflammatory Properties of Activated Platelets.TH open : companion journal to thrombosis and haemostasis · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Patrick M SiegelDepartment of Cardiology and Angiology I, Faculty of Medicine, University Heart Center Freiburg - Bad Krozingen, University of Freiburg, Freiburg, Germany.
Laura SanderAtherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.
Alba FrickeAtherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.
Johannes StammAtherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.
Xiaowei WangAtherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.
Prerna SharmaAtherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.
Nicole BasslerAtherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.
Ya-Lan YingAtherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.
Christoph B OlivierDepartment of Cardiology and Angiology I, Faculty of Medicine, University Heart Center Freiburg - Bad Krozingen, University of Freiburg, Freiburg, Germany.
Steffen U EisenhardtAtherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, VIC, 3004, Australia.
Christoph BodeDepartment of Cardiology and Angiology I, Faculty of Medicine, University Heart Center Freiburg - Bad Krozingen, University of Freiburg, Freiburg, Germany.
Ingo AhrensDepartment of Cardiology and Angiology I, Faculty of Medicine, University Heart Center Freiburg - Bad Krozingen, University of Freiburg, Freiburg, Germany.
Philipp DiehlDepartment of Cardiology and Angiology I, Faculty of Medicine, University Heart Center Freiburg - Bad Krozingen, University of Freiburg, Freiburg, Germany.
Karlheinz PeterDepartment of Cardiology and Angiology I, Faculty of Medicine, University Heart Center Freiburg - Bad Krozingen, University of Freiburg, Freiburg, Germany. karlheinz.peter@baker.edu.au.
Baker Heart and Diabetes Institute · AUUniversity of Freiburg · DEMonash University · AUKrankenhaus der Augustinerinnen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

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Indexed as

Acute Coronary SyndromeAdenosine DiphosphateAnti-Inflammatory AgentsCase-Control StudiesCoronary Artery DiseaseHumansInflammationMacrophagesMonocytesPhosphorylationPurinergic P2Y Receptor AntagonistsReceptors, Purinergic P2Y12THP-1 CellsAdenosine DiphosphateAnti-Inflammatory AgentsPurinergic P2Y Receptor AntagonistsReceptors, Purinergic P2Y12

Identifiers

PMID34465804
PMCPMC8408182
OpenAlexW3197508512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.