Evidence map›Paper›PMID 34465780›Full record

ArticleNature communications2021

Predicting post-operative right ventricular failure using video-based deep learning.

Rohan Shad, Nicolas Quach, Robyn Fong, Patpilai Kasinpila, Cayley Bowles, Miguel Castro, Ashrith Guha, Erik E Suarez, Stefan Jovinge, Sangjin Lee and 10 more

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. A wearable non-invasive sonogenetic pacemaker.Nature biomedical engineering · 2026
    Article
  5. Review
  6. A generalizable deep learning system for cardiac MRI.Nature biomedical engineering · 2026
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. A Multi-Task Deep Learning Model for Pediatric Echocardiography Analysis.medRxiv : the preprint server for health sciences · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Rohan Shad *Department of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.ORCID 0000-0002-0453-9041
Nicolas Quach *Department of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.ORCID 0000-0002-6792-5185
Robyn FongDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Patpilai KasinpilaDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Cayley BowlesDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Miguel CastroDepartment of Cardiovascular Medicine, Houston Methodist DeBakey Heart Centre, Houston, TX, USA.
Ashrith GuhaDepartment of Cardiovascular Medicine, Houston Methodist DeBakey Heart Centre, Houston, TX, USA.
Erik E SuarezDepartment of Cardiothoracic Surgery, Houston Methodist DeBakey Heart Centre, Houston, TX, USA.
Stefan JovingeDepartment of Cardiovascular Surgery, Spectrum Health Grand Rapids, Grand Rapids, MI, USA.ORCID 0000-0002-8446-0228
Sangjin LeeDepartment of Cardiovascular Surgery, Spectrum Health Grand Rapids, Grand Rapids, MI, USA.
Theodore BoeveDepartment of Cardiovascular Surgery, Spectrum Health Grand Rapids, Grand Rapids, MI, USA.
Myriam AmsallemDepartment of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.
Xiu TangDepartment of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.
Francois HaddadDepartment of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-9648-7671
Yasuhiro ShudoDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Y Joseph WooDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.ORCID 0000-0002-2506-492X
Jeffrey TeutebergDepartment of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.
John P CunninghamDepartment of Statistics, Columbia University, New York, NY, USA.ORCID 0000-0001-9125-3027
Curtis P LanglotzStanford Artificial Intelligence in Medicine Centre, Stanford, CA, USA.ORCID 0000-0002-8972-8051
William HiesingerDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA. willhies@stanford.edu.ORCID 0000-0002-3548-2578

Funding

Stanford Integrated Cardiovascular/Pulmonary Residency Research Training ProgramR38HL143615 · NHLBI · STANFORD UNIVERSITY · PI Michael Peter Fischbein, Marlene Rabinovitch · 2020 to 2026
$2.2M
NHLBI NIH HHS R38 HL143615
6 · The paper itself

Abstract

Despite progressive improvements over the decades, the rich temporally resolved data in an echocardiogram remain underutilized. Human assessments reduce the complex patterns of cardiac wall motion, to a small list of measurements of heart function. All modern echocardiography artificial intelligence (AI) systems are similarly limited by design - automating measurements of the same reductionist metrics rather than utilizing the embedded wealth of data. This underutilization is most evident where clinical decision making is guided by subjective assessments of disease acuity. Predicting the likelihood of developing post-operative right ventricular failure (RV failure) in the setting of mechanical circulatory support is one such example. Here we describe a video AI system trained to predict post-operative RV failure using the full spatiotemporal density of information in pre-operative echocardiography. We achieve an AUC of 0.729, and show that this ML system significantly outperforms a team of human experts at the same task on independent evaluation.

Indexed as

Deep LearningEchocardiographyHeartHeart FailureHumansPostoperative PeriodPreoperative CareRetrospective StudiesVentricular Dysfunction, RightVideo Recording

Identifiers

PMID34465780
PMCPMC8408163

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.