ReviewNPJ schizophrenia2021
More than a biomarker: could language be a biosocial marker of psychosis?
Review in NPJ schizophrenia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Voice Patterns as Markers of Schizophrenia: Building a Cumulative Generalizable Approach Via a Cross-Linguistic and Meta-analysis Based Investigation.Schizophrenia bulletin · 2023Pooled it
- Natural language processing in clinical neuroscience and psychiatry: A review.Frontiers in psychiatry · 2022Pooled it
- Cross-linguistic benchmarking of NLP metrics for psychosis research.NPJ digital medicine · 2026Article
- Speech and Language Markers of Bipolar Disorder: Challenges and Opportunities.Bipolar disorders · 2026Review
- Automated Speech-Based Modeling of Item-Level Symptom Severity in Schizophrenia.JAMA network open · 2026Article
- Vocal Markers of Schizophrenia: Assessing the Generalizability of Machine Learning Models and Their Clinical Applicability.Schizophrenia bulletin · 2026Article
- Linking speech patterns to brain structure in affective and psychotic disorders: an integrative natural language processing approach.Molecular psychiatry · 2026Article
- Rethinking language, cognition and assessment in psychosis: How bilingualism challenges psychiatry and how natural language processing can help.Schizophrenia (Heidelberg, Germany) · 2026Review
- Setting digital psychiatry in motion: towards dynamic digital markers for digital phenotyping.NPP - digital psychiatry and neuroscience · 2026Review
- Grounding psychosis research: why observable signs should anchor biological investigations.Frontiers in psychiatry · 2026Article
- Network analysis of relationships among psychopathology, cognitive function, and psychosocial functioning in independent samples of Chinese with schizophrenia or bipolar disorder.Psychological medicine · 2025Article
- Large language models in clinical psychiatry: Applications and optimization strategies.World journal of psychiatry · 2025Review
- Glutamate, Contextual Insensitivity, and Disorganized Speech in First-Episode Schizophrenia: A 7T Magnetic Resonance Spectroscopy Study.Biological psychiatry global open science · 2025Article
- Quantitative semiology: harnessing AI-generated teaching signals in psychiatry.Journal of psychiatry & neuroscience : JPN · 2025Article
- Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech.Translational psychiatry · 2025Article
- Associations of Vocal Features, Psychiatric Symptoms, and Cognitive Functions in Schizophrenia.Neuropsychiatric disease and treatment · 2025Article
- Speech analytics across the schizophrenia spectrum disorders: multimodal natural language processing and machine learning modelling in a Chinese-speaking population.Frontiers in psychiatry · 2025Article
- Latent mechanisms of language disorganization relate to specific dimensions of psychopathology.Nature. Mental health · 2024Article
- Theory-Driven Analysis of Natural Language Processing Measures of Thought Disorder Using Generative Language Modeling.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Speech characteristics yield important clues about motor function: Speech variability in individuals at clinical high-risk for psychosis.Schizophrenia (Heidelberg, Germany) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Automated extraction of quantitative linguistic features has the potential to predict objectively the onset and progression of psychosis. These linguistic variables are often considered to be biomarkers, with a large emphasis placed on the pathological aberrations in the biological processes that underwrite the faculty of language in psychosis. This perspective offers a reminder that human language is primarily a social device that is biologically implemented. As such, linguistic aberrations in patients with psychosis reflect both social and biological processes affecting an individual. Failure to consider the sociolinguistic aspects of NLP measures will limit their usefulness as digital tools in clinical settings. In the context of psychosis, considering language as a biosocial marker could lead to less biased and more accessible tools for patient-specific predictions in the clinic.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.