Evidence map›Paper›PMID 34465585›Full record

ArticleMolecular cancer research : MCR2021

Identification of a Novel

Megann A Boone, Cenny Taslim, Jesse C Crow, Julia Selich-Anderson, Mike Watson, Peter Heppner, James Hamill, Andrew C Wood, Stephen L Lessnick, Mark Winstanley

Abstract readCase Reports
In one paragraph

Article in Molecular cancer research : MCR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Megann A BooneBiomedical Sciences Graduate Program, College of Medicine, The Ohio State University, Columbus, Ohio.ORCID 0000-0002-7806-8027
Cenny TaslimCenter for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.ORCID 0000-0003-3302-9099
Jesse C CrowCenter for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Julia Selich-AndersonCenter for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio.
Mike WatsonLabPLUS, Auckland City Hospital, Grafton, Auckland, New Zealand.
Peter HeppnerStarship Children's Hospital, Grafton, Auckland, New Zealand.
James HamillStarship Children's Hospital, Grafton, Auckland, New Zealand.ORCID 0000-0003-4269-7291
Andrew C WoodStarship Children's Hospital, Grafton, Auckland, New Zealand.ORCID 0000-0003-4850-6345
Stephen L LessnickBiomedical Sciences Graduate Program, College of Medicine, The Ohio State University, Columbus, Ohio. stephen.lessnick@nationwidechildrens.org.ORCID 0000-0001-9645-4434
Mark WinstanleyStarship Children's Hospital, Grafton, Auckland, New Zealand.

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Project 2: Evaluating the dynamic protein-protein interactions mediated by LCDs within EWS/FLI and its partners in living cells via single molecule imagingU54CA231641 · NCI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI LESSNICK, STEPHEN L. · 2018 to 2018
$6.2M
NCI NIH HHS P30 CA016058NCI NIH HHS U54 CA231641
6 · The paper itself

Abstract

Ewing sarcoma is a pediatric bone cancer defined by a chromosomal translocation fusing one of the FET family members to an ETS transcription factor. There have been seven reported chromosomal translocations, with the most recent reported over a decade ago. We now report a novel FET/ETS translocation involving

Indexed as

HumansInfant, NewbornOncogene Proteins, FusionProto-Oncogene Proteins c-etsRNA-Binding Protein FUSSarcoma, EwingTranslocation, GeneticETV4 protein, humanFUS protein, humanOncogene Proteins, FusionProto-Oncogene Proteins c-etsRNA-Binding Protein FUS

Identifiers

PMID34465585
PMCPMC8568690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.