Evidence map›Paper›PMID 34465572›Full record

ArticleRespiratory care2021

Respiratory Mechanics in a Cohort of Critically Ill Subjects With COVID-19 Infection.

August Longino, Toni Riveros, Erik Risa, Chris Hebert, Joshua Krieger, Steven Coppess, Flynn McGuire, Pavan K Bhatraju, James Town, Nicholas J Johnson

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Prone positioning in COVID-19 ARDS: more pros than cons.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

August LonginoDivision of General Internal Medicine, University of Colorado, Aurora, Colorado. August.Longino@cuanschutz.edu.
Toni RiverosDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington Medical Center, Seattle, Washington.
Erik RisaSchool of Medicine, University of Washington Medical Center, Seattle, Washington.
Chris HebertDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington Medical Center, Seattle, Washington.
Joshua KriegerDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington Medical Center, Seattle, Washington.
Steven CoppessDepartment of Emergency Medicine, University of Washington Medical Center, Seattle, Washington.
Flynn McGuireSchool of Medicine, University of Washington Medical Center, Seattle, Washington.
Pavan K BhatrajuDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington Medical Center, Seattle, Washington.
James TownDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington Medical Center, Seattle, Washington.
Nicholas J JohnsonDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington Medical Center, Seattle, Washington.
University of Washington Medical Center · USUniversity of Colorado Anschutz Medical Campus · US

Funding

The Assessment of Acute Kidney Injury Sub-phenotypes in the Intensive Care UnitK23DK116967 · NIDDK · UNIVERSITY OF WASHINGTON · PI BHATRAJU, PAVAN KUMAR · 2019 to 2023
$938k
NIDDK NIH HHS K23 DK116967
6 · The paper itself

Abstract

backgroundPatients with coronavirus disease 2019 (COVID-19) often develop acute hypoxemic respiratory failure and receive invasive mechanical ventilation. Much remains unknown about their respiratory mechanics, including the trajectories of pulmonary compliance and [Formula: see text]/[Formula: see text], the prognostic value of these parameters, and the effects of prone positioning. We described respiratory mechanics amon

methodsWe included patients with COVID-19 who were mechanically ventilated between February and May 2020. Daily values of pulmonary compliance, [Formula: see text], [Formula: see text], and the use of prone positioning were abstracted from electronic medical records. The trends were analyzed separately over days 1-10 and days 1-35 of intubation, stratified by prone positioning use, survival, and initial [Formula: see text]/[Formula: see text].

resultsAmong 49 subjects on mechanical ventilation day 1, the mean compliance was 41 mL/cm H

conclusionsRespiratory mechanics of the subjects with COVID-19 who were on mechanical ventilation were characterized by persistently low respiratory system compliance and [Formula: see text]/[Formula: see text], similar to ARDS due to other etiologies. The [Formula: see text]/[Formula: see text] was more tightly associated with mortality than with compliance.

Indexed as

COVID-19Respiratory Distress SyndromeCritical IllnessHumansProne PositionRespiration, ArtificialRespiratory MechanicsSARS-CoV-2COVID-19hypoxemic respiratory failuremechanical ventilationoxygenationPaO2/FIO2/ ratiopneumoniaprone positioningpulmonary complianceSARS-CoV-2viral

Identifiers

PMID34465572
PMCPMC8576110
OpenAlexW3198563230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.