Evidence map›Paper›PMID 34465422›Full record

ArticleTransplantation proceedings2021

Association of Inflammatory Biomarkers with Immunosuppression Management and Outcomes in Kidney Transplant Recipients with COVID-19.

Nashila AbdulRahim, Meredith McAdams, Pin Xu, David Wojciechowski, Ricardo M La Hoz, Christopher Lu, Miguel A Vazquez, S Susan Hedayati

Open access · hybridAbstract read
In one paragraph

Article in Transplantation proceedings, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nashila AbdulRahimDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas; Parkland Hospital and Health System, Dallas, Texas.
Meredith McAdamsDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas. Electronic address: meredith.mcadams@utsouthwestern.edu.
Pin XuDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
David WojciechowskiDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Ricardo M La HozDivision of Infectious Diseases and Geographic Medicine, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Christopher LuDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Miguel A VazquezDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas; Parkland Hospital and Health System, Dallas, Texas.
S Susan HedayatiDivision of Nephrology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
The University of Texas Southwestern Medical Center · USParkland Health & Hospital System · USSouthwestern Medical Center · US

Funding

RENAL CONTROL OF BODY COMPOSITION AND BLOOD PRESSURET32DK007257 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI BAUM, MICHEL GERARD, MOE, ORSON W · 1986 to 2021
$5.0M
NIDDK NIH HHS T32 DK007257
6 · The paper itself

Abstract

backgroundKidney transplant recipients with coronavirus disease 2019 (COVID-19) are at increased risk for adverse outcomes, such as acute kidney injury (AKI), intensive care unit (ICU) admission, and death. The association of inflammatory biomarkers with outcomes and the impact of changes in immunosuppression on biomarker levels are unknown.

methodsWe investigated factors associated with a composite of AKI, ICU admission, or death, and whether immunosuppression changes correlated with changes in inflammatory biomarkers and outcomes in kidney transplant recipients with a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction.

resultsOf 59 patients, 50% had estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m

conclusionsKidney transplant recipients with COVID-19 have high rates of ICU admissions, AKI, and death. Those with eGFR<60 mL/min/1.73 m

Indexed as

COVID-19Immunosuppression TherapyKidney TransplantationAcute Kidney InjuryAdultAgedBiomarkersFemaleHumansMaleMiddle AgedRetrospective StudiesTransplant RecipientsUnited StatesBiomarkers

Identifiers

PMID34465422
PMCPMC8349691
OpenAlexW3188114554

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.