Trial reportCritical care (London, England)2021
Comprehensive versus standard care in post-severe acute kidney injury survivors, a randomized controlled trial.
Trial report in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04012008 (Standard Versus Comprehensive Care for Post Acute Kidney Injury), which is not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Standard Versus Comprehensive Care for Post Acute Kidney Injury: A Randomized Controlled Trial
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sex and gender considerations in randomized controlled trials in critical care nephrology: a meta-epidemiologic study.BMC medicine · 2025Pooled it
- The Effectiveness of Pharmacist Interventions in the Management of Patient with Renal Failure: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Telemedicine versus Face-to-Face Follow-Up in Post-Acute Kidney Injury Survivors: A Pilot Randomized Controlled Trial.Kidney360 · 2026Trial
- Examining variations in adherence to guideline-recommended post-acute kidney injury care in primary care in England: a population-based cohort study.BMC medicine · 2026Article
- Nephrologist follow-up improves outcomes after hospitalization with acute kidney injury.BMC nephrology · 2026Article
- Transitions of care following acute kidney injury: a systems-based analysis.BMC nephrology · 2026Article
- Top ten tips to manage patients after acute kidney injury.Clinical kidney journal · 2026Review
- SGLT2 Inhibitors and Long-Term Outcomes After AKI.Kidney international reports · 2026Article
- The global epidemiology of acute kidney injury: challenges and opportunities.Nature reviews. Nephrology · 2026Review
- Implementing the Acute Kidney Injury in Care Transitions (ACT) Program: Results From a Mixed Methods Feasibility Study.Kidney medicine · 2026Article
- Assessing renal recovery after acute kidney injury in elderly patients: a retrospective cohort study.Renal failure · 2025Article
- State of the art: Renal recovery after AKI - from basic science to clinical practice.Intensive care medicine · 2025Review
- Epidemiology and long-term outcomes of critically ill patients with severe AKI in India and Southeast Asia.Intensive care medicine · 2025Article
- The burden of acute kidney disease: an epidemiological review and importance of follow-up care.Clinical kidney journal · 2025Review
- ASN Kidney Health Guidance on the Outpatient Management of Patients with Dialysis-Requiring Acute Kidney Injury.Journal of the American Society of Nephrology : JASN · 2025Article
- Acute Kidney Injury Care Following Hospitalization: Care Provision and Public Policy for Acute Kidney Injury Survivors.Advances in kidney disease and health · 2025Review
- Acute Kidney Injury in Care Transitions (ACT): A Randomized Controlled Feasibility Trial.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2025Article
- Advancing Community Care and Access to Follow-Up after Acute Kidney Injury Hospitalization: A Randomized Clinical Trial.Journal of the American Society of Nephrology : JASN · 2025Article
- Postdischarge Care of Acute Kidney Injury Survivors: An Opportunity for Targeted Nurse and Pharmacist Interventions.Advances in kidney disease and health · 2025Review
- Care That Fits: Optimizing Value-Based Care for Acute Kidney Injury Survivors.Advances in kidney disease and health · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrently, there is a lack of evidence to guide optimal care for acute kidney injury (AKI) survivors. Therefore, post-discharge care by a multidisciplinary care team (MDCT) may improve these outcomes. This study aimed to demonstrate the outcomes of implementing comprehensive care by a MDCT in severe AKI survivors.
methodsThis study was a randomized controlled trial conducted between August 2018 to January 2021. Patients who survived severe AKI stage 2-3 were enrolled and randomized to be followed up with either comprehensive or standard care for 12 months. The comprehensive post-AKI care involved an MDCT (nephrologists, nurses, nutritionists, and pharmacists). The primary outcome was the feasibility outcomes; comprising of the rates of loss to follow up, 3-d dietary record, drug reconciliation, and drug alert rates at 12 months. Secondary outcomes included major adverse kidney events, estimated glomerular filtration rate (eGFR), and the amount of albuminuria at 12 months.
resultsNinety-eight AKI stage 3 survivors were enrolled and randomized into comprehensive care and standard care groups (49 patients in each group). Compared to the standard care group, the comprehensive care group had significantly better feasibility outcomes; 3-d dietary record, drug reconciliation, and drug alerts (p < 0.001). The mean eGFR at 12 months were comparable between the two groups (66.74 vs. 61.12 mL/min/1.73 m
conclusionsComprehensive care by an MDCT is feasible and could be implemented for severe AKI survivors. MDCT involvement also yields better reduction of the UACR and better blood pressure control. Trial registration Clinicaltrial.gov: NCT04012008 (First registered July 9, 2019).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.