Evidence map›Paper›PMID 34465136›Full record

ArticleAIDS research and human retroviruses2022

Endothelial Cells Promote Productive HIV Infection of Resting CD4

Catherine M Card, Bernard Abrenica, Lyle R McKinnon, Terry Blake Ball, Ruey-Chyi Su

Open access · hybridAbstract read
In one paragraph

Article in AIDS research and human retroviruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. The immunophenotype and proviral landscape of HIV-infected CD4 T cells during antiretroviral therapy.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Journal of virology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Catherine M CardJC Wilt Infectious Diseases Research Center, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.ORCID 0000-0002-2561-9649
Bernard AbrenicaJC Wilt Infectious Diseases Research Center, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Lyle R McKinnonDepartment of Medical Microbiology & Infectious Diseases, University of Manitoba, Winnipeg, Canada.ORCID 0000-0002-7157-0700
Terry Blake BallJC Wilt Infectious Diseases Research Center, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Ruey-Chyi SuJC Wilt Infectious Diseases Research Center, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.
Public Health Agency of Canada · CAUniversity of Nairobi · KE

Funding

CIHR 154043
6 · The paper itself

Abstract

Resting CD4

Indexed as

Endothelial CellsHIV InfectionsCD4-Positive T-LymphocytesCell AdhesionHumansIntercellular Adhesion Molecule-1Lymphocyte Function-Associated Antigen-1T-LymphocytesVascular Cell Adhesion Molecule-1Intercellular Adhesion Molecule-1Lymphocyte Function-Associated Antigen-1Vascular Cell Adhesion Molecule-1CD4+ T cellendothelial cellHIV susceptibilityintegrinLFA-1VLA-4

Identifiers

PMID34465136
PMCPMC8861939
OpenAlexW3196616700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.