ArticleJournal of the American Heart Association2021
Cardiac Arrhythmias and Impaired Heart Rate Variability in Older Patients With Ventricular Septal Defects.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Health and Well-Being in Older Adults With a Surgically Closed or an Unrepaired Ventricular Septal Defect.Journal of the American Heart Association · 2023Trial
- Monitoring heart rhythms in adult males with X-linked ichthyosis using wearable technology: a feasibility study.Archives of dermatological research · 2025Article
- Transcatheter closure of perimembranous ventricular septal defects in elderly patients and risk factors of postoperative arrhythmias.Frontiers in cardiovascular medicine · 2025Article
- Cardiac arrhythmia in individuals with steroid sulfatase deficiency (X-linked ichthyosis): candidate anatomical and biochemical pathways.Essays in biochemistry · 2024Review
- Cardiac autonomic dysfunction in adult congenital heart disease.BMC cardiovascular disorders · 2023Article
- Late surgical ventricular septal defect closure in a low middle-income country setting: a case series.Journal of medical case reports · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Congenital ventricular septal defects (VSDs) are considered to have benign long-term outcome when treated correctly in childhood. However, abnormal parameters are described in younger adults, including impaired heart rate variability (HRV). It is not known whether such abnormalities will deteriorate with age. Therefore, HRV and cardiac events, such as premature ventricular contraction, were evaluated in patients aged >40 years with congenital VSDs and compared with healthy peers. Methods and Results A total of 30 surgically closed VSDs (51±8 years, repair at median age 6.3 years with total range 1.4-54 years) with 30 healthy controls (52±9 years) and 30 small, unrepaired VSDs (55±12 years) with 30 controls (55±10 years) were all equipped with a Holter monitor for 24 hours. Compared with healthy peers, surgically closed patients had lower SD of the normal-to-normal (NN) interbeat interval (129±37 versus 168±38 ms;
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