Evidence map›Paper›PMID 34465123›Full record

ArticleCirculation. Heart failure2021

Psychometric Evaluation of the Kansas City Cardiomyopathy Questionnaire in Men and Women With Heart Failure.

Vittal Hejjaji, Yuanyuan Tang, Theresa Coles, Philip G Jones, Bryce B Reeve, Robert J Mentz, Erica S Spatz, Shannon M Dunlay, Brittany Caldwell, Anindita Saha and 6 more

Open access · greenAbstract read
In one paragraph

Article in Circulation. Heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Investigating gender-based differential item functioning on the Kansas City Cardiomyopathy Questionnaire (KCCQ) using qualitative content analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Vittal HejjajiSaint Luke's Mid America Heart Institute/University of Missouri-Kansas City (V.H., Y.T., P.G.J., A.T., K.K.P., J.A.S.).ORCID 0000-0002-4323-040X
Yuanyuan TangSaint Luke's Mid America Heart Institute/University of Missouri-Kansas City (V.H., Y.T., P.G.J., A.T., K.K.P., J.A.S.).
Theresa ColesDuke Clinical Research Institute, Durham, NC (T.C., B.B.R., R.J.M., D.H.).ORCID 0000-0003-2941-8999
Philip G JonesSaint Luke's Mid America Heart Institute/University of Missouri-Kansas City (V.H., Y.T., P.G.J., A.T., K.K.P., J.A.S.).ORCID 0000-0002-7136-4464
Bryce B ReeveDuke Clinical Research Institute, Durham, NC (T.C., B.B.R., R.J.M., D.H.).ORCID 0000-0002-6709-8714
Robert J MentzDuke Clinical Research Institute, Durham, NC (T.C., B.B.R., R.J.M., D.H.).
Erica S SpatzYale University School of Medicine, New Haven, CT (E.S.S.).ORCID 0000-0002-1557-7713
Shannon M DunlayMayo Clinic College of Medicine, Rochester, MN (S.M.D.). Center for Devices and Radiological Health, US FDA, White Oak, MD.
Brittany Caldwell
Michelle E Tarver
Andy TranSaint Luke's Mid America Heart Institute/University of Missouri-Kansas City (V.H., Y.T., P.G.J., A.T., K.K.P., J.A.S.).
Krishna K PatelSaint Luke's Mid America Heart Institute/University of Missouri-Kansas City (V.H., Y.T., P.G.J., A.T., K.K.P., J.A.S.).ORCID 0000-0003-0512-8444
Debra HenkeDuke Clinical Research Institute, Durham, NC (T.C., B.B.R., R.J.M., D.H.).
Ileana L Piña
John A SpertusSaint Luke's Mid America Heart Institute/University of Missouri-Kansas City (V.H., Y.T., P.G.J., A.T., K.K.P., J.A.S.).ORCID 0000-0002-2839-2611
Saint Luke's Hospital · USClinical Research Institute · USCenter for Devices and Radiological Health · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
CARDIOVASCULAR OUTCOMES RESEARCH TRAINING PROGRAMT32HL110837 · NHLBI · UNIVERSITY OF MISSOURI KANSAS CITY · PI JOHN A SPERTUS · 2012 to 2026
$5.0M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS T32 HL110837
6 · The paper itself

Abstract

backgroundThe Kansas City Cardiomyopathy Questionnaire (KCCQ) has been psychometrically evaluated in multiple heart failure (HF) populations, but the comparability of its psychometric properties between men and women is unknown.

methodsData from 3 clinical trials (1 in stable HF with preserved ejection fraction, 1 each in stable and acute HF with reduced ejection fraction) and 1 prospective cohort study (stable HF with reduced ejection fraction), incorporating 6773 men and 3612 women with HF, were used to compare the construct validity, internal and test-retest reliability, ability to detect change, predict mortality and hospitalizations and minimally important differences between the 2 sexes. Interactions of the KCCQ overall summary and subdomain scores by sex were independently examined.

resultsThe KCCQ-Overall Summary score correlated well with New York Heart Association functional class in both sexes across patients with stable (correlation coefficient: -0.40 in men versus -0.49 in women) and acute (-0.37 in men versus -0.34 in women) HF. All KCCQ subdomains demonstrated concordant relationships with relevant comparison standards with no significant interactions by sex in 19 of 21 of these construct validity analyses. All KCCQ scores were equally predictive and other psychometric evaluations showed similar results by sex: test-retest reliability (intraclass correlation coefficient 0.94 in men versus 0.92 in women), responsive to change (standardized response mean 1.01 in both sexes), as were the minimally important differences and internal reliability.

conclusionsThe psychometric properties of the KCCQ, in terms of validity, prognosis, reliability, and sensitivity to change, are comparable in men and women with HF with preserved ejection fraction and HF with reduced ejection fraction.

Indexed as

PsychometricsSex FactorsSurveys and QuestionnairesAgedCardiomyopathiesFemaleHealth StatusHeart FailureHumansKansasMaleMiddle AgedQuality of LifeReproducibility of ResultsStroke VolumeVentricular Function, Leftcardiomyopathieshealth statusheart failurehospitalizationquestionnaire

Identifiers

PMID34465123
PMCPMC8806967
OpenAlexW3197099700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.