ArticleDiabetes & metabolism journal2022
Association between Metabolic Syndrome and Microvascular Complications in Chinese Adults with Type 1 Diabetes Mellitus.
Article in Diabetes & metabolism journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 19 citations in OpenAlex.
- Systemic Inflammatory Markers in Patients with Metabolic Syndrome with and Without Dry Eye Disease: An Observational Comparative Study.Diagnostics (Basel, Switzerland) · 2026Article
- Review
- Uric acid to high-density lipoprotein cholesterol ratio is associated with the prevalence of diabetic kidney disease in euthyroid patients with type 1 diabetes mellitus in China: A multicenter cross-sectional study.Journal of diabetes investigation · 2025Article
- Link Between Metabolic Syndrome, Inflammation, and Eye Diseases.International journal of molecular sciences · 2025Review
- Metabolic syndrome in type 1 diabetes: higher time above range and glycemic variability revealed by continuous glucose monitoring (CGM).Diabetology & metabolic syndrome · 2025Article
- Current status, trend changes, and future predictions of the disease burden of type 1 diabetes kidney disease in global and China.Frontiers in endocrinology · 2025Article
- Article
- Simplified integration of optimal self-management behaviors is associated with improved HbA1c in patients with type 1 diabetes.Journal of endocrinological investigation · 2024Observational
- Correlation between triglyceride-glucose index and diabetic kidney disease risk in adults with type 1 diabetes mellitus.Diabetology & metabolic syndrome · 2024Article
- Article
- Association of Endotoxemia with Low-Grade Inflammation, Metabolic Syndrome and Distinct Response to Lipopolysaccharide in Type 1 Diabetes.Biomedicines · 2023Article
- Development and validation of an age-sex-ethnicity-specific metabolic syndrome score in the Chinese adults.Nature communications · 2023Article
- Article
- Association between Metabolic Syndrome and Microvascular Complications in Chinese Adults with Type 1 Diabetes Mellitus (Diabetes Metab J 2022;46:93-103).Diabetes & metabolism journal · 2022Article
- Association between Metabolic Syndrome and Microvascular Complications in Chinese Adults with Type 1 Diabetes Mellitus (Diabetes Metab J 2022;46:93-103).Diabetes & metabolism journal · 2022Article
- Metabolic syndrome associated with higher glycemic variability in type 1 diabetes: A multicenter cross-sectional study in china.Frontiers in endocrinology · 2022Article
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11 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundBoth type 1 diabetes mellitus (T1DM) and metabolic syndrome (MetS) are associated with an elevated risk of morbidity and mortality yet with increasing heterogeneity. This study primarily aimed to evaluate the prevalence of MetS among adult patients with T1DM in China and investigate its associated risk factors, and relationship with microvascular complications.
methodsWe included adult patients who had been enrolled in the Guangdong T1DM Translational Medicine Study conducted from June 2010 to June 2015. MetS was defined according to the updated National Cholesterol Education Program criterion. Logistic regression models were used to estimate the odds ratio (OR) for the association between MetS and the risk of diabetic kidney disease (DKD) and diabetic retinopathy (DR).
resultsAmong the 569 eligible patients enrolled, the prevalence of MetS was 15.1%. While female gender, longer diabetes duration, higher body mass index, and glycosylated hemoglobin A1c (HbA1c) were risk factors associated with MetS (OR, 2.86, 1.04, 1.14, and 1.23, respectively), received nutrition therapy education was a protective factor (OR, 0.46). After adjustment for gender, age, diabetes duration, HbA1c, socioeconomic and lifestyle variables, MetS status was associated with an increased risk of DKD and DR (OR, 2.14 and 3.72, respectively; both P<0.05).
conclusionAlthough the prevalence of MetS in adult patients with T1DM in China was relatively low, patients with MetS were more likely to have DKD and DR. A comprehensive management including lifestyle modification might reduce their risk of microvascular complications in adults with T1DM.
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