ArticleClinical nutrition (Edinburgh, Scotland)2021
Handgrip strength as a surrogate marker of lean mass and risk of malnutrition in paediatric patients.
Article in Clinical nutrition (Edinburgh, Scotland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Pooled it
- Impact of critical illness and withholding of early parenteral nutrition in the pediatric intensive care unit on long-term physical performance of children: a 4-year follow-up of the PEPaNIC randomized controlled trial.Critical care (London, England) · 2022Trial
- Altitude and child development: A cross-sectional comparative study of children in urbanized low-altitude and rural high-altitude settings in Kyrgyzstan.Physiological reports · 2026Article
- Hand Grip Strength at 4.5 Years of Age After Complex Cardiac Surgery in Early Infancy.Pediatric cardiology · 2026Article
- Fat-Free Mass Predictions From Anthropometrics in South African Prepubertal Children.Journal of paediatrics and child health · 2026Article
- Comparative evaluation of nutritional risk screening tools in hospitalized children with acute gastroenteritis.Frontiers in nutrition · 2026Article
- Morphofunctional markers to assess disease-related pediatric malnutrition at admission and their association with length of hospital stay.Frontiers in nutrition · 2026Article
- Low birth weight and intrauterine growth restriction and their relationship with handgrip strength in adolescents.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2026Article
- The Relationship of Handgrip Strength to Body Composition and Cardiopulmonary Fitness in Children and Young Adults.Journal of pediatrics. Clinical practice · 2025Article
- Sarcopenia in children and adolescents submitted to hematopoietic stem cell transplantation.Hematology, transfusion and cell therapy · 2024Article
- Muscle Wasting among Hospitalized Children: A Narrative Review of the Feasibility and Accuracy of Diagnostic Methods.Children (Basel, Switzerland) · 2023Review
- Malnutrition Patterns in Children with Chronic Kidney Disease.Life (Basel, Switzerland) · 2023Review
- Review
- Hand grip strength should be normalized by weight not height for eliminating the influence of individual differences: Findings from a cross-sectional study of 1,511 healthy undergraduates.Frontiers in nutrition · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND &
aimsThe use of handgrip strength (HGS) as a proxy of nutritional status in sick children has not been studied. This study created HGS centile charts in healthy children and explored the utility of HGS z-scores as markers of body composition and screening of malnutrition risk in sick children.
methodsData from 535 healthy children aged 5-16 years were used for the development of HGS centiles adjusted either for age or height. In 595 sick children, relationships between HGS z-scores with body composition, malnutrition risk (Paediatric Yorkhill Malnutrition Score-PYMS), length of hospital stay (LOS) and biomarkers of disease severity were explored. The use of HGS z-score to identify sick children in need of further dietetic assessment was investigated.
resultsChildren scoring at high malnutrition risk with PYMS had lower HGS z-scores for age (by 0.51 SD, p < 0.001) and height (by 0.46 SD, p = 0.001) than those who scored low. A HGS z-score at cut-offs of -0.81 SD and -1.2 SD for age and height, respectively, was predictive of need for dietetic intervention in sick children with sensitivity of 79% and 70% and specificity of 56% and 69%, respectively. HGS z-scores were predictive of fat free mass (FFM) in sick and healthy (all p < 0.001) children, while fat mass was not. HGS z-scores were inversely related with plasma CRP (rho, age: -0.21; height: -0.23, both p = 0.001). HGS was not predictive of LOS.
conclusionHGS is predictive of FFM, could compliment assessment of malnutrition risk, and may help identify children for further dietetic intervention on admission to hospital.
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