Trial reportAmerican journal of respiratory and critical care medicine2021
Effects of Inhaled Corticosteroid/Long-Acting β
Abstract readClinical Trial
In one paragraph
Trial report in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 77 citations in OpenAlex.
- The role of the respiratory microbiome in acute and chronic respiratory diseases.Nature reviews. Microbiology · 2026Review
- Review
- Targeting Elastin-Derived Peptides Reverses Alveolar Epithelial Dysfunction in Chronic Obstructive Pulmonary Disease.MedComm · 2026Article
- Inhaled Corticosteroids Influence Pulmonary Microbiota in Severe Equine Asthma.Animals : an open access journal from MDPI · 2026Article
- Characteristics of Respiratory Microbiome in COPD-A Literature Review.Advances in respiratory medicine · 2026Review
- Effects of Inhaled Corticosteroids/Long-Acting Beta-Agonists (ICS/LABA) on Airway Microbial Diversity and IL-8/IL-10 Cytokine Levels in Stable COPD.Combinatorial chemistry & high throughput screening · 2026Article
- The gut-lung axis: pathological crosstalk and inter-organ communication in chronic obstructive pulmonary disease and inflammatory bowel disease.Frontiers in immunology · 2026Review
- Crosstalk between the microbiome and the mucosal immunoglobulin A system in the lung, in health and disease.Frontiers in cellular and infection microbiology · 2026Review
- Pharyngeal Microbiota in Pre-COPD and COPD: Associations with Clinical Pattern and Respiratory Infection.Biomedicines · 2025Article
- Type 2 inflammation in chronic obstructive pulmonary disease: A promising treatable trait and practice recommendations.Chinese medical journal pulmonary and critical care medicine · 2025Article
- Investigation of the Number of Oral Bacteria in Patients with Chronic Obstructive Pulmonary Disease, Asthma, and Asthma and Chronic Obstructive Pulmonary Disease Overlap.Internal medicine (Tokyo, Japan) · 2025Article
- The Canadian Lung Outcomes in Users of Vaping Devices (CLOUD) Study: protocol for a prospective, observational cohort study.BMJ open · 2025Article
- Post-viral lung diseases: the microbiota as a key player.ERJ open research · 2025Review
- Nebulization of 2% lidocaine has no detectable impact on the healthy equine respiratory microbiota.PloS one · 2025Article
- Targeting Immunoproteasome in Polarized Macrophages Ameliorates Experimental Emphysema Via Activating NRF1/2-P62 Axis and Suppressing IRF4 Transcription.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- DNA Methylation Demonstrates Bronchoalveolar Cell Senescence in People Living with HIV: An Observational Cohort Study.Biomedicines · 2024Article
- Tobacco use, self-reported professional dental cleaning habits, and lung adenocarcinoma diagnosis are associated with bronchial and lung microbiome alpha diversity.Respiratory research · 2024Article
- Inhaled Corticosteroids in Subjects with Chronic Obstructive Pulmonary Disease: An Old, Unfinished History.Biomolecules · 2024Review
- Exploring the influence of the microbiome on the pharmacology of anti-asthmatic drugs.Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
- Lung microbiome: new insights into the pathogenesis of respiratory diseases.Signal transduction and targeted therapy · 2024Review
Corrections and comments
- Commented on by
Authors and funding
18 authors at 7 institutions in 4 countries.
Fernando Sergio Leitao FilhoCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Hiroto TakiguchiCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Kentaro AkataCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Seung Won RaCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Ji-Yong MoonCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Hyun Kuk KimCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Yuji ChoCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Kei YamasakiCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Stephen MilneCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Julia YangCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Cheng Wei Tony YangCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Xuan LiCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Corey NislowFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Stephan F van EedenCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Tawimas ShaipanichCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Stephen LamCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Janice M LeungCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
Don D SinCentre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
St. Paul's Hospital · CAUniversity of Occupational and Environmental Health Japan · JPBC Cancer Agency · CAThe University of Sydney · AUTokai University · JPUlsan College · KRUniversity of British Columbia · CA
Funding
CIHR
Abstract
PubMed holds no abstract for this paper.
Indexed as
Drug CombinationsAdministration, InhalationAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAdultAgedAged, 80 and overFemaleHumansMaleMicrobiotaMiddle AgedPulmonary Disease, Chronic ObstructiveReceptors, Adrenergic, beta-2Treatment OutcomeAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsDrug CombinationsReceptors, Adrenergic, beta-216S rRNA geneairway microbiomeCOPDinhaled corticosteroids
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.