ArticleAmerican journal of respiratory and critical care medicine2021
Integrated Biomarkers for the Management of Indeterminate Pulmonary Nodules.
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Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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67citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
67 citing papers in PubMed, 94 citations in OpenAlex.
- A Real-World Assessment of Stage I Lung Cancer Through Electronic Nose Technology.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2024Trial
- Development and validation of machine learning diagnostic models integrating clinical, CT, and laboratory features to differentiate lung cancer from pulmonary tuberculosis in patients with solitary pulmonary nodules: a single-center retrospective study.Translational lung cancer research · 2026Article
- Leveraging Commercially Available Protein Assays as Biomarkers for Lung Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Recent advances in artificial intelligence across interventional pulmonology: a narrative review.Journal of thoracic disease · 2026Review
- Theoretical Clinical Utility of Advanced Practice Provider Use of an Artificial Intelligence Radiomics-based Tool for Pulmonary Nodule Evaluation and Management.CHEST pulmonary · 2026Article
- Evaluation of Lung Cancer Probability Models and Guideline Recommendations in Settings With a High Prevalence of Cancer.CHEST pulmonary · 2026Article
- Article
- Diagnosis model of early malignant pulmonary nodules based on clinical laboratory data.Scientific reports · 2026Article
- Validation of a blood-based autoantibody test to assess lung cancer risk in 4-30 mm pulmonary nodules: a retrospective pooled analysis of four cohort studies.Future oncology (London, England) · 2026Article
- The value of an integrated multi-omics model in the diagnosis of benign and malignant pulmonary nodules.Translational cancer research · 2026Article
- Longitudinal Analysis of CYFRA 21-1 Levels in Patients with Pulmonary Nodules: Differential Trajectories Between Benign and Malignant Cases and Impact of Tumor Resection.medRxiv : the preprint server for health sciences · 2026Article
- Article
- AI-assisted clinico-quantitative imaging nomogram for preoperative malignancy risk in solid and part-solid pulmonary nodules ≤ 3 cm: development and internal validation.Frontiers in oncology · 2026Article
- Evaluation of DNA Methylation in TAC1, SOX17, and RASSF1A for the Early Diagnosis of Lung Cancer.Cancer management and research · 2026Article
- Preoperative evaluation of solitary pulmonary nodules and adenocarcinoma invasiveness using ultra-high-resolution computed tomography and multidimensional liquid biopsy: a prospective exploratory study.Frontiers in oncology · 2026Article
- Predictive Factors and Nomogram for Malignant Pulmonary Nodules (≤ 1 cm).Canadian respiratory journal · 2026Article
- Identification of PIWI-interacting RNAs based models for lung adenocarcinoma early detection: a multicenter cohort study.Molecular biomedicine · 2025Article
- Article
- Biomarkers for the diagnosis of indeterminate pulmonary nodules: are we there yet?Journal of thoracic disease · 2025Review
- Application of liquid biopsy in differentiating lung cancer from benign pulmonary nodules (Review).International journal of molecular medicine · 2025Review
7 more citing papers are in PubMed but not listed here.
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Authors and funding
39 authors at 11 institutions in 1 country.
Michael N KammerDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.ORCID 0000-0001-7912-8450
Dhairya A LakhaniDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.ORCID 0000-0001-7577-1887
Aneri B BalarDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.
Sanja L AnticDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.
Amanda K KussrowDepartment of Chemistry, and.
Rebekah L WebsterDepartment of Chemistry, and.
Shayan MahapatraDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.ORCID 0000-0003-4259-580X
Udaykamal BaradDivision of Radiology, and.
Chirayu ShahDivision of Radiology, and.
Thomas AtwaterDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.
Brenda DiergaardeDepartment of Human Genetics, Graduate School of Public Health, University of Pittsburgh and UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.ORCID 0000-0002-3578-6547
Jun QianDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.
Alexander KaizerDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado.ORCID 0000-0003-2334-5514
Melissa NewPulmonary Sciences and Critical Care.
Erin HirschDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
William J FeserDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Jolene StrongBiomedical Informatics and Personalized Medicine, and.
Matthew RiothMedical Oncology and Biomedical Informatics and Personalized Medicine, School of Medicine, University of Colorado, Aurora, Colorado.
York E MillerPulmonary Sciences and Critical Care.
Yoganand BalagurunathanH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.ORCID 0000-0002-5598-4727
Dianna J RoweDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.
Sherif HelmeyDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.
Sheau-Chiann ChenDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-5574-1434
Joseph BauzaAmerican College of Radiology, Philadelphia, Pennsylvania.
Stephen A DeppenDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.ORCID 0000-0002-3661-662X
Kim SandlerDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.
Fabien MaldonadoDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.
Avrum SpiraDepartment of Medicine, Boston University, Boston, Massachusetts.ORCID 0000-0003-1467-0489
Ehab BillatosDepartment of Medicine, Boston University, Boston, Massachusetts.ORCID 0000-0002-6645-1758
Matthew B SchabathH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.ORCID 0000-0003-3241-3216
Robert J GilliesH. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.ORCID 0000-0002-8888-7747
David O WilsonDepartment of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; and.
Ronald C WalkerDivision of Radiology, and.ORCID 0000-0003-2470-6764
Bennett LandmanDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.ORCID 0000-0001-5733-2127
Heidi ChenAmerican College of Radiology, Philadelphia, Pennsylvania.
Eric L GroganDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.ORCID 0000-0002-3886-9399
Anna E BarónDepartment of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Darryl J BornhopDepartment of Chemistry, and.
Pierre P MassionDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine.
Pulmonary and Allergy Associates · USColorado School of Public Health · USVanderbilt University · USMoffitt Cancer Center · USAmerican College of Radiology · USBoston University · USPulmonary and Critical Care Associates · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Pittsburgh Medical Center · USUPMC Hillman Cancer Center · USVanderbilt University Medical Center · US
Funding
VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTOPHER J. BAKKENIST · 1988 to 2026
$158.0MTissue Bank and Biomarkers CoreP50CA058187 · NCI · UNIVERSITY OF COLORADO DENVER · PI DEGREGORI, JAMES V · 1992 to 2018
$43.8MValidation of Biomarkers of Risk for the Early Detection of Lung CancerU01CA152662 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DEPPEN, STEPHEN, GROGAN, ERIC L · 2010 to 2025
$12.8MQuantitative Imaging Clinical Validation Center at Moffitt Cancer CenterU01CA200464 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI JOHN J HEINE, Matthew B. Schabath · 2016 to 2026
$9.2MRadiomics of NSCLCU01CA143062 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI GILLIES, ROBERT J., SCHABATH, MATTHEW B. · 2010 to 2020
$5.7MClinical Utility of Biomarkers Driven Management of Indeterminate Pulmonary NodulesR01CA252964 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric L Grogan, Alexander Mark Kaizer · 2021 to 2026
$3.3MRandomized Clinical Trial of Lung Cancer Chemoprevention with Sulforaphane in Former SmokersR01CA213123 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI YUAN, JIAN-MIN · 2017 to 2021
$3.2MUltrasensitive Detection of Tumor Specific DNA Methylation Changes for the Early Detection of Lung Cancer U01CA214165 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HERMAN, JAMES G., WANG, TZA-HUEI JEFF · 2016 to 2021
$3.1MNon-invasive evaluation of indeterminate pulmonary nodulesU01CA186145 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MASSION, PIERRE P. · 2015 to 2019
$2.0MNCI NIH HHS P30 CA047904NCI NIH HHS P50 CA058187NCI NIH HHS R01 CA213123NCI NIH HHS R01 CA252964NCI NIH HHS U01 CA143062NCI NIH HHS U01 CA152662NCI NIH HHS U01 CA186145NCI NIH HHS U01 CA200464NCI NIH HHS U01 CA214165
Abstract
PubMed holds no abstract for this paper.
Indexed as
AgedBiomarkersCarcinomaCase-Control StudiesCohort StudiesFemaleHumansLung NeoplasmsMaleMiddle AgedMultiple Pulmonary NodulesPredictive Value of TestsRisk FactorsROC CurveTomography, X-Ray ComputedBiomarkersbiomarkersdiagnostic imaginglung neoplasmstumor
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.