Evidence map›Paper›PMID 34464214›Full record

Observational studyJournal of managed care & specialty pharmacy2021

Factors associated with primary nonadherence to newly initiated direct oral anticoagulants in patients with nonvalvular atrial fibrillation.

Alethea Charlton, Xavier Vidal, Mònica Sabaté, Elena Bailarín, Lina María Leguízamo Martínez, Luisa Ibáñez

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of managed care & specialty pharmacy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Adherence to oral thromboprophylaxis in atrial fibrillation: an overview for clinicians.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Review
  4. Article
  5. Not obtaining a medication the first time it is prescribed: primary non-adherence to cardiovascular pharmacotherapy.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Optimization of DOAC management services in a centralized anticoagulation clinic.Research and practice in thrombosis and haemostasis · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Alethea CharltonFundació Institut Català de Farmacologia (FICF), Hospital Vall d'Hebron, Barcelona, Spain; Institute for Medical Information Processing, Biometry and Epidemiology, LMU Munich, Munich, Germany; and Pettenkofer School of Public Health, Munich, Germany.
Xavier VidalFundació Institut Català de Farmacologia (FICF), Hospital Vall d'Hebron; Autonomous University of Barcelona; and Clinical Pharmacology Department, Vall d'Hebron University Hospital, Barcelona, Spain.
Mònica SabatéFundació Institut Català de Farmacologia (FICF), Hospital Vall d'Hebron; Autonomous University of Barcelona; and Clinical Pharmacology Department, Vall d'Hebron University Hospital, Barcelona, Spain.
Elena BailarínFundació Institut Català de Farmacologia (FICF) and Clinical Pharmacology Department, Vall d'Hebron University Hospital, Barcelona, Spain.
Lina María Leguízamo MartínezAutonomous University of Barcelona and Clinical Pharmacology Department, Vall d'Hebron University Hospital, Barcelona, Spain.
Luisa IbáñezFundació Institut Català de Farmacologia (FICF), Hospital Vall d'Hebron; Autonomous University of Barcelona; and Clinical Pharmacology Department, Vall d'Hebron University Hospital, Barcelona, Spain.
Hebron University · PSSociedad Española de Farmacología Clínica · ESZimmer Biomet (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Medication AdherenceAdministration, OralAgedAged, 80 and overAnticoagulantsAtrial FibrillationDabigatranDatabases, FactualFemaleHumansMaleMiddle AgedRetrospective StudiesRivaroxabanStrokeWarfarinAnticoagulantsDabigatranRivaroxabanWarfarin

Identifiers

PMID34464214
PMCPMC10391044
OpenAlexW3197089278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.